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中国儿童及青少年遗尿症患病率的Meta分析

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目的 系统评价中国儿童及青少年遗尿症患病率.方法 计算机检索CNKI、WanFangData、VIP、SinoMed、PubMed、Embase、Web of Science数据库,搜集关于中国儿童及青少年遗尿症患病率的横断面研究,检索时限均从建库至2023年11月.由2名评价员独立筛选文献、提取数据并评价纳入研究的偏倚风险后,应用R软件进行Meta分析,采用baujat图、亚组分析探讨异质性来源,采用逐一剔除法进行敏感性分析.结果 共纳入38篇文献,包括327 065例研究对象,其中遗尿症患儿18 392名,合并患病率为5.59%[95%CI(4.58%,6.81%)].遗尿症患病率随年龄升高呈明显下降趋势,5岁、12岁、18岁患病率分别为12.30%[95%CI(9.96%,15.11%)]、2.07%[95%CI(1.68%,2.56%)]和 1.95%[95%CI(0.90%,4.20%)].男童患病率 6.36%[95%CI(5.49%,7.36%)]高于女童 4.30%[95%CI(3.57%,5.16%)].使用 DSM-Ⅳ 为诊断标准的患病率为 3.78%[95%CI(2.58%,5.52%)],以ICCS为诊断标准的患病率为5.99%[95%CI(4.75%,7.52%)].结论 中国儿童及青少年遗尿症患病率受地区、年龄、性别、诊断标准的影响,华南地区患病率更高,患病率随年龄升高而降低,男性患病率高于女性.
Prevalence of nocturnal enuresis among Chinese children and adolescents:a meta-analysis
Objective To systematically review the prevalence of enuresis in Chinese children and adolescents.Methods A computer search was conducted for epidemiological research on the prevalence of enuresis among Chinese children and adolescents in databases including CNKI,WanFang Data,VIP,SinoMed,PubMed,Embase,and Web of Science.Two researchers independently carried out literature screening,data extraction,and quality evaluation.Meta-analysis was executed using R language,with baujat plots and subgroup analysis to investigate heterogeneity sources,and leave-one-out for sensitivity analysis.Results A total of 38 papers were included,encompassing 327 065 participants,with 18 392 children suffering from enuresis.The aggregate prevalence rate was 5.59%(95%CI 4.58%to 6.81%).The prevalence rate showed a significant decreasing trend with increasing age,with rates at ages 5,12,and 18 being 12.30%(95%CI 9.96%to 15.11%),2.07%(95%CI 1.68%to 2.56%),and 1.95%(95%CI 0.90%to 4.20%),respectively.The incidence rate in male children was higher at 6.36%(95%CI 5.49%to 7.36%)than that in female children at 4.30%(95%CI 3.57%to 5.16%).Using DSM-Ⅳ as the diagnostic criteria,the prevalence rate was 3.78%(95%CI 2.58%to 5.52%),while it was 5.99%(95%CI 4.75%to 7.52%)using ICCS as the criteria.Conclusion The prevalence of enuresis among Chinese children and adolescents is affected by factors such as region,age,gender,and diagnostic standards.The prevalence is higher in South China,decreases with age,and is significantly higher in males than in females.

Nocturnal enuresisPrevalenceMeta-analysisChildrenAdolescents

王文、王喆、姜浩然、王明月、郑三霞

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山东中医药大学第一临床医学院(济南 250355)

山东中医药大学针灸推拿学院(济南 250355)

河南中医药大学儿科医学院(郑州 450046)

山东中医药大学第二附属医院儿科(济南 250011)

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遗尿症 患病率 Meta分析 儿童 青少年

山东省名老中医药专家传承工作室建设项目

鲁卫函[2019]92号

2024

中国循证医学杂志
四川大学

中国循证医学杂志

CSTPCD北大核心
影响因子:1.761
ISSN:1672-2531
年,卷(期):2024.24(9)
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