Objective We constructed a real-world evidence evaluation system to provide reference for obtaining high-quality evidence in evidence-based medicine.Methods Through the investigation and analysis of the key factors influencing the real-world research evidence,combined with domestic and foreign literature and evaluation tools,we preliminarily constructed the indicators of the real-world evidence evaluation system,then consulted experts in related fields by the Delphi method,modified and determined the final evaluation indicators.Results The indicators of the final real-world evidence evaluation system included 40 items.The recovery efficiencies of the two rounds of expert consultation were 88.2％and 100％;The expert coordination coefficients were 0.174(P＜0.001)and 0.189(P＜0.001).After the second round of consultation,the mean of Likert scale in the range of 3.73～4.93,and the coefficient of variation varied in the range of 0.05～0.21.Conclusion The real-world evidence evaluation system constructed in this study has certain reliability and scientificity,which can provide a basis and help for the transformation of real-world research into high-quality evidence.
关键词
真实世界证据/德尔菲法/质量评价/偏倚识别
Key words
Real-world evidence/Delphi/Quality evaluation/Identification of bias
维普
万方数据