Pharmaceutical excipients,as an indispensable part of drug preparation,play crucial roles as drug carriers,improving drug release,ensuring drug stability,and enhancing patient compliance.Traditional Chinese Medicine(TCM)boasts a rich developmental history.With the modernization of technology,the deep integration of pharmacy,chemistry,and materials science has provided broader opportunities for innovative research in TCM.Simultaneously,the demand for high-quality excipients has become increasingly critical.This paper aims to review current research and applications of excipients in TCM preparations,including pre-mixed and co-processed excipients,modified excipients,and the unification of drugs and excipients,such as flavoring agents,fillers,penetration enhancers,and delivery systems.A meticulous synthesis and analysis of existing research aims to provide a reference for selecting excipients in TCM preparations,stimulate innovation in excipient development for TCM,and advocate for the development of personalized excipients.
关键词
药用辅料/中药制剂/预混与共处理辅料/改性辅料/药辅合一
Key words
pharmaceutical excipients/traditional Chinese medicine preparations/pre-mixed and co-processed excipients/modified excipients/unification of drugs and excipients