首页|太极康复六式训练治疗慢性疲劳综合征心脾两虚证的临床疗效及其对机体氧化应激的影响

太极康复六式训练治疗慢性疲劳综合征心脾两虚证的临床疗效及其对机体氧化应激的影响

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目的:探讨太极康复六式训练治疗慢性疲劳综合征(chronic fatigue syndrome,CFS)心脾两虚证的临床疗效及对机体氧化应激的影响.方法:随机将60例CFS心脾两虚证患者分为治疗组(n=30)与对照组(n=30).对照组患者给予归脾丸治疗,治疗组患者在对照组的基础上增加太极康复六式训练.比较治疗前、治疗4周、治疗8周、随访4周两组患者的中医症状积分及疲劳量表-14(FS-14)评分;于治疗前及治疗 8 周检测患者血清中超氧化物歧化酶(superoxide dismutase,SOD)、谷胱甘肽过氧化物酶(glutathione peroxidase,GSH-Px)活性和丙二醛(malondialdehyde,MDA)含量.结果:对两组患者治疗期间不同时间点的中医症状积分及FS-14评分进行重复测量方差分析,结果显示:两组患者的中医症状积分和FS-14评分的时间效应、组间效应及交互效应差异均具有统计学意义(P<0.05).组内比较显示:两组患者中医症状积分和FS-14评分随时间而改变.组间比较显示:治疗组治疗4周、治疗8周以及随访4周的中医症状积分均低于对照组(P<0.01);治疗组治疗8周以及随访4周的FS-14评分低于对照组(P<0.01).治疗8周后治疗组血清SOD活性高于对照组(P<0.05),MDA含量低于对照组(P<0.05).治疗组总有效率93.10%(27/29),高于对照组的72.41%(21/29),差异有统计学意义(P<0.05).结论:太极康复六式训练有助于改善CFS心脾两虚证患者躯体疲劳及精神疲劳症状,提高抗氧化能力,进而辅助提高临床疗效.
The clinical efficacy of Tai Chi rehabilitation six-style training in treating chronic fatigue syndrome with concurrent heart and spleen deficiency,and its impact on oxidative stress
Objective To evaluate the clinical effectiveness of Tai Chi rehabilitation six-style train-ing in treating chronic fatigue syndrome(CFS)and its impact on oxidative stress.Methods Sixty pa-tients diagnosed as CFS and cardiosplenic deficiency syndrome were randomly divided into a treatment group(n=30)and a control group(n=30).Both groups took Gui Pi Pills,while the treatment group was additionally provided with the Tai Chi rehabilitation six-style training.Before the treatment,as well as after 4-and 8-week treatment,and 4-week follow-up,both groups were evaluated using Tra-ditional Chinese Medicine(TCM)symptom scale and Fatigue Scale-14(FS-14).Before and after 8-week treatment,both groups were measured the superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and malondialdehyde(MDA)in their serum.Results Repeated measures ANOVA showed that there were significant differences between the two groups in the time effect,intergroup effect and inter-action effect of the TCM symptom score and FS-14 score.The scores of TCM symptoms after 4-and 8-week treatment,and 4-week follow-up,and the FS-14 scores after 8-week treatment and 4-week follow-up in the treatment group were significantly lower than those in the control group(P<0.01).Moreover,after 8 weeks of treatment,the serum SOD activity of the treatment group was significantly higher than the control group(P<0.05),and the content of MDA was significantly lower than the latter group(P<0.05).In addition,the total effective rate in the treatment group was 93.10%(27/29),signifi-cantly higher than 72.41%of the control group(21/29)(P<0.05).Conclusion Tai Chi rehabilitation six-style training helps to relieve physical and mental fatigue symptoms in CFS patients with heart and spleen deficiency syndrome,enhance their antioxidant capacity,thereby improving clinical outcomes.

chronic fatigue syndromegongfa/Tai Chi rehabilitation six-style trainingclinical effi-cacyoxidative stress

杨尚林、林巧婷、钟叶蓓、李洪亮、马思源、裴鑫、杨小慧、杨舟、李铁浪

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湖南中医药大学针灸推拿与康复学院(长沙 410208)

湖南中医药大学第一附属医院针灸科(长沙 410007)

慢性疲劳综合征 功法/太极康复六式训练 临床疗效 氧化应激

湖南省自然科学基金湖南省教育厅重点项目湖南省大学生创新创业训练计划湖南省中医药科研项目

2023JJ3045422A0273S2022105410272017124

2024

中国运动医学杂志
中国体育科学学会

中国运动医学杂志

CSTPCD北大核心
影响因子:0.856
ISSN:1000-6710
年,卷(期):2024.43(2)
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