摘要
本文结合文献与个人经验总结了黄斑、视盘旁与周边脉络膜新生血管(CNV)的临床表现与治疗.黄斑CNV:本文重点讨论了那些对抗血管内皮生长因子(VEGF)治疗无反应患者的原因及对策;并介绍了息肉样脉络膜血管病变(PCV)的光学相干层析成像(OCT)的特征及目前的最佳治疗方案.视盘旁CNV:介绍了本病眼底表现,荧光素眼底血管造影(FFA)及OCT所见,常见病因及治疗.周边CNV:则介绍了临床表现、疾病转归,治疗及预后特别是与脉络膜黑色素瘤的鉴别诊断做了较详尽的讨论.并简短提到,近期研究认为周边渗出性出血性脉络膜视网膜病变(PEHCR)可能属于厚脉络膜频谱病群中的一员.
Abstract
Based on the literature and personal experience,this paper summarizes the clinical manifestations and treatment of macular,parapillary and peripheral choroidal neovascularization(CNV).For macular CNV,the article focuses on the causes and countermeasures of those treated with anti-vascular endothelial growth factor(VEGF)but without response.As for polypoidal choroidal vasculopathy(PCV),the characteristic findings of optical coherence tomography(OCT)may take a role of screening before indocyanine green angiograph(ICGA).The optimal management for PCV recently is intravitreal injection of anti-VEGF combined with photodynamic therapy(PDT).The author also describes the fundus manifestation,fluorescein angiography(FFA),OCT findings,as well as various etiology,intervention and prognosis of parapillary CNV.For the peripheral CNV,clinical manifestation,management,differential diagnosis especially with choroid melanoma are discussed in detail.A recent research which suggested that Peripheral exudative hemorrhagic chorioretinopathy(PEHCR)might be a member of pacychoroidal spectrum disease is briefly mentioned in the paper.
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维普
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