Objective To analyze the clinical features of male papillary thyroid micro carcinoma(PTMC)and the risk factors of central lymph node metastasis(CLNM).Methods A total of 743 patients with PTMC who had undergone primary operation in our department from January 2018 to December 2022 were retrospectively analyzed,with 152 male patients as the study group and 591 female patients as the control group.The clinical and pathological data of the two groups were compared.Univariate and multivariate statistical methods were used to analyze the risk factors of CLNM in male PTMC patients.Results There were no significant differences in age,maximum tumor diameter,multifocal tumor,tumor distribution and lateral cervical lymph node metastasis between the two groups(P＞0.05),but there were significant differences in tumor capsule invasion,combined with Hashimoto thyroiditis(HT)and CLNM between the two groups(P＜0.01).Univariate analysis showed that the maximum tumor diameter＞5 mm,multi-focal,bilateral distribution and capsule invasion were risk factors for CLNM in male PTMC patients,while binary Logistic multivariate regression analysis showed that the maximum tumor diameter＞5 mm and capsule invasion were independent risk factors for CLNM in male PTMC patients.Conclusion Male PTMC patients are more prone to capsule invasion and CLNM.Special attention should be paid to the central lymph nodes dissection of male PTMC patients especially those with tumor maximum diameter＞5 mm or capsular invasion.
维普
万方数据