中国眼耳鼻喉科杂志2024,Vol.24Issue(2) :128-133.DOI:10.14166/j.issn.1671-2420.2024.02.009

儿童眼眶占位性病变287例临床分布特征分析

Clinical distribution feature of orbital space-occupying disease in children:a clinical study on 287 patients

张少波 王萍 王海龙 叶飞飞 李娜 李养军
中国眼耳鼻喉科杂志2024,Vol.24Issue(2) :128-133.DOI:10.14166/j.issn.1671-2420.2024.02.009

儿童眼眶占位性病变287例临床分布特征分析

Clinical distribution feature of orbital space-occupying disease in children:a clinical study on 287 patients

张少波 1王萍 1王海龙 1叶飞飞 2李娜 1李养军1
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作者信息

  • 1. 空军军医大学第二附属医院眼科 西安 710038
  • 2. 商洛市中心医院眼科 商洛 726000
  • 折叠

摘要

目的 探讨儿童眼眶占位性病变的病种分类和疾病分布特征.方法 回顾性病例系列研究.收集2012年1月—2022年6月空军军医大学第二附属医院眼科收治入院的287例儿童眼眶占位性病变的临床资料,按照Shields分类方法,以不同性别和年龄对眼眶良、恶性疾病进行分类,分析疾病的病种分类及分布特征.结果 287例儿童眼眶占位性病变中,良性病变占91.29%,恶性病变占8.71%.良性病变以囊性病变、血管性病变、神经源性肿瘤等为主,其中皮样囊肿最多见.恶性病变以肌源性肿瘤、淋巴造血系统肿瘤为主,其中横纹肌肉瘤最常见.儿童眼眶占位性病变多见于0~4岁,其中皮样囊肿、毛细血管瘤的发病率与年龄具有相关性(P<0.05).病变性质与性别的相关性不显著,但朗格汉斯细胞组织细胞增生症、皮样囊肿、毛细血管瘤、横纹肌肉瘤等多见于男性患者.结论 儿童眼眶占位性病变与成人的疾病分布不同,主要以先天性和胚胎性病变为主.良性病变以皮样囊肿为主,恶性病变以横纹肌肉瘤为主,部分疾病具有明显的年龄和性别倾向.

Abstract

Objective To investigate the classification and distribution features of orbital space-occupying diseases in children.Methods A retrospective case series study was conducted.The clinical data of 287 pediatric patients with orbital space-occupying diseases admitted to the Department of Ophthalmology at the Second Affiliated Hospital of the Air Force Military Medical University from January 2012 to June 2022 were collected.According to the Shields classification method,the benign and malignant orbital diseases were classified by gender and age,and the classification and distribution features of these diseases were analyzed.Results Among 287 children with orbital space-occupying diseases,91.29%were benign diseases and 8.71%were malignant diseases.Benign diseases mainly included cystic lesions,vascular lesions,neurogenic tumors,among which dermoid cysts were the most common.The malignant diseases mainly consisted of myogenic tumors and lymphohematopoietic system tumors,among which rhabdomyosarcoma was the most common.Orbital space-occupying lesions in children were mostly found in 0-4 years old,and the incidence rate of dermoid cysts and capillary hemangiomas was significantly correlated with age(P<0.05).The correlation between the nature of the lesion and gender is not significant,however,Langerhans cell histiocytosis,dermoid cysts,capillary hemangiomas,and rhabdomyosarcoma were more common in male patients.Conclusions The clinical distribution pattern of orbital space-occupying diseases in children is different from that observed in adults,it is mainly composed of congenital and embryonic diseases.Benign lesions are predominantly characerized by dermatoid cysts while rhabdomyosarcoma prevails among malignant cases.Certain diseases exhibit distinct age or gender predilections.

关键词

儿童/眼眶占位性病变/病种分类/疾病分布特征

Key words

Child/Orbital space-occupying disease/Disease classification/Clinical distribution feature

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出版年

2024
中国眼耳鼻喉科杂志
复旦大学附属眼耳鼻喉科医院

中国眼耳鼻喉科杂志

CSTPCD
影响因子:0.555
ISSN:1671-2420
参考文献量23
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