Optic neuritis(ON)is characterized by inflammatory lesions involving the optic nerve,with idiopathic optic neuritis being the main subtype.In recent years,a deeper understanding of idiopathic optic neuritis led to the identification of additional diseases corresponding changes in treatment approaches.Furthermore,biological immunotherapy has entered a new era,with some treatments recommended as first-line options according to relevant guidelines.This article introduces and summarizes the standardized application and progress of biological agents in ON,especially in idiopathic demyelinating optic neuritis,aiming to provide a reference for standardized treatment.
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