Neuro-endoscopy techniques mainly include endoscopic transnasal skull base surgery,endoscopic ventricular surgery,endoscopic transcranial keyhole surgery and endoport surgery et al.Among them,endoscopic transnasal skull base surgery has been wildly utilized for removing tumors localized in sellar region.Due to the neuro-ophthalmologic disorders involving the visual afferent system(presented with visual loss and/visual field defect)and efferent system(presented with diplopia/ophthalmoplegia),the location of optic canal,orbital apex,cavernous sinus,skull base are usually involved,in which the neuro-anatomy are complicated and blood vessels are abundant.The routine craniotomy surgery usually leads to serious complications and trauma.With the utilizing of neuro-endoscopy methods,optic nerve decompression,sellar and skull base tumor removal,cavernous sinus biopsy and third ventriculostomy are widely promoted due to its minimal side effects.In this article,we reviewed the update literatures and summarized the multidisciplinary study result of neuro-ophthalmologic division in Eye Ear Nose and Throat Hospital of Shanghai in recent years.