Objective To compare the differences in set-up errors between human eye positioning and artificial intelligence(AI)positioning guided by fan-beam CT(FBCT)during radiotherapy for head and neck tumors(HNT).Methods FBCT guided radiotherapy(FBCT-RT)was routinely used for HNT treatment on uRT-linac 506c accelerator.FBCT scans were carried out at specific intervals,including the first three fractions and then once a week.The set-up errors were analyzed in three dimensions.The second FBCT scan was performed using only AI positioning without visual calibration(experimental group),while the third FBCT scan was implemented using human positioning(control group).Self-compared t-test was used to compare the set-up errors and positioning time of the two groups.Analysis of variance was used to compare the set-up errors under AI positioning during the six-week course of radiotherapy.Thirty-five HNT patients were enrolled in the study from September 2022 to November 2022.Results The set-up errors in vertical direction(VRT),longitudinal direction(LNG)and lateral direction(LAT)direction were all statistically significant(P<0.05)between the two groups.It was found that set-up errors could be stably controlled with AI positioning during the first three weeks of radiotherapy for all patients.However,instability of VRT occurred during the last three weeks of radiotherapy for malignancies(P<0.05),althrough set-up accuracy remained stable for orbital tumors.Conclusions AI positioning guided by FBCT not only saved set-up time but also reduced set-up errors during earlier stages of radiotherapy.Compared with other HNTs,orbital benign tumors benefited most from AI positioning due to lower set-up errors.
关键词
头颈肿瘤/智能摆位/摆位误差/扇形束CT引导放疗
Key words
Head and neck tumor/Artificial intelligence positioning/Set-up errors/Fan-beam CT guided radiotherapy