首页|顶空气相色谱法测定口服液体药用聚酯瓶中乙醛残留量

顶空气相色谱法测定口服液体药用聚酯瓶中乙醛残留量

扫码查看
原文链接
  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
  • 维普
目的:建立口服液体药用聚酯瓶中乙醛残留量的测定方法.方法:采用顶空气相色谱法.色谱柱为DB-FFAP毛细管柱,氢火焰离子化检测器,进样口温度为200℃,检测器温度为200℃,载气为氮气；顶空进样器平衡温度为70℃,平衡时间为30 min,程序升温.结果:乙醛检测浓度线性范围为0.002～0.02 mg·L-1(r=0.999 1),平均回收率为98.37％,RSD=2.82％(n=6),检测限为0.1ng.结论:本方法准确可靠,可用于口服液体药用聚酯瓶中乙醛的限度检查.
Determination of Residual Acetaldehyde in Oral Liquid PET Bottle by Headspace Gas Chromatography
OBJECTIVE: To establish the method for determination of residual acetaldehyde in oral liquid PET bottle. METHODS: Headspace gas chromatography was adopted. The determination was performed on DB-FFAP capillary column. FID detector was used with injector temperature of 200 ℃ and detector temperature of 200 ℃ using nitrogen as carrier gas. The equilibrium temperature of headspace sampling was set at 70 t with equilibrium time of 30 min by programmed temperature. RESULTS: The linear range of acetaldehyde was 0.002~0.02 mg·L-1 (r=0.999 Dwith average recovery of 98.37% (RSD=2.82%, n=6). The detection limit was 0.1 ng. CONCLUSION: The method is accurate, relibale and can be used for determination of the limit of acetaldehyde in oral liquid PET bottle.

Headspace gas chromatographyOral liquid PET bottleAcetaldehydeResidual

李瑞生、崔勇和、李林

展开 >

襄阳市中心医院,湖北襄阳441021

顶空气相色谱法 口服液体药用聚酯瓶 乙醛 残留量

2012

10.6039/j.issn.1001-0408.2012.29.26

中国药房
中国医院协会,中国药房杂志社

中国药房

CSTPCDCSCD
影响因子：0.956
ISSN：1001-0408
年,卷(期)：2012.23(29)
  • 2