Metabolic syndrome(MS)is a complex group of clinical syndromes with obesity,abnormal glucose and lipid metabolism and hypertension as the main clinical features.Swertia mussotii is a commonly used medicine among the Tibetan people in China.Its efficacy is consistent with the pathogenesis of MS,which has the potential for symptomatic treatment of MS.It is found that effective ingredients such as gentiopicroside,sweroside,swertiamarin,mangiferin,and oleanolic acid can improve MS by regulating glucose and lipid metabolism,improving obesity,regulating the cardiovascular system,inhibiting chronic inflammation,oxidative stress,endoplasmic reticulum and autophagy,and improving intestinal microflora disorder.
关键词
藏茵陈/有效成分/代谢综合征/肥胖/糖脂代谢/作用机制
Key words
Swertia mussotii/active ingredients/metabolic syndrome/obesity/glucose and lipid metabolism/mechanism of action