Research progress on the improvement mechanism of active ingredients of Swertia mussotii on metabolic syndrome
Metabolic syndrome(MS)is a complex group of clinical syndromes with obesity,abnormal glucose and lipid metabolism and hypertension as the main clinical features.Swertia mussotii is a commonly used medicine among the Tibetan people in China.Its efficacy is consistent with the pathogenesis of MS,which has the potential for symptomatic treatment of MS.It is found that effective ingredients such as gentiopicroside,sweroside,swertiamarin,mangiferin,and oleanolic acid can improve MS by regulating glucose and lipid metabolism,improving obesity,regulating the cardiovascular system,inhibiting chronic inflammation,oxidative stress,endoplasmic reticulum and autophagy,and improving intestinal microflora disorder.
Swertia mussotiiactive ingredientsmetabolic syndromeobesityglucose and lipid metabolismmechanism of action