Construction and application of anticoagulant pharmacy service model based on the integrated theory of health behavior change
OBJECTIVE To establish anticoagulation pharmaceutical service model based on the integrated theory of health behavior change (ITHBC),and analyze its effects. METHODS Referring to relevant literature and soliciting opinions from 8 experts from departments such as pharmacy,respiratory medicine,and vascular surgery,a anticoagulation pharmaceutical service model based on ITHBC was ultimately formed. VTE inpatients were selected from The First Affiliated Hospital of Shihezi University from December 2023 to June 2024 as the research subjects. They were randomly assigned into intervention group (58 cases) and control group (60 cases) using a random number table method. The intervention group implemented pharmacist-led anticoagulant pharmaceutical service model based on ITHBC,while the control group adopted a conventional anticoagulant pharmaceutical service model. The anticoagulation-related outcomes of two groups were compared after 3 months:anticoagulation compliance rate,the incidence of adverse drug reactions,the score of medication adherence and compliance rate of anticoagulant prescription;economic evaluation was conducted. RESULTS After implementing ITHBC-based anticoagulant pharmaceutical services for 3 months,the intervention group had higher anticoagulation compliance rate,score of medication adherence,and compliance rate of anticoagulant prescription than the control group (P<0.05). There was no statistically significant difference in the total incidence of adverse drug reactions between the two groups (P>0.05). For every 1％ point increase in anticoagulant compliance rate,the hospital needed to invest 4.35 yuan additionally in anticoagulant pharmaceutical service fees. Compared with China's per capita gross domestic product (GDP,89358 yuan) in 2023,the incremental cost-effectiveness ratio value that increased the anticoagulation compliance rate by 50％ is far less than one time of per capita GDP. CONCLUSIONS The pharmacist-led anticoagulant pharmaceutical service model based on ITHBC can effectively improve the outcomes of anticoagulant therapy for VTE patients,enhance medication compliance,improve patients' awareness and recognition of adverse drug reactions to anticoagulants,and has certain economic and social benefits.
integrated theory of health behavior changevenous thromboembolismanticoagulant therapypharmaceutical caremedication compliance
万方数据
维普
