OBJECTIVE To provide a reference for pharmaceutical care in patients with hemorrhagic transformation after cerebral infarction complicated with atrial fibrillation.METHODS Clinical pharmacists participated in the treatment practice of a patient with hemorrhagic transformation after cerebral infarction complicated with atrial fibrillation.Because the patient had a hemorrhagic transformation after cerebral infarction after stent implantation and arterial thrombolysis,the clinical pharmacists recommended stopping antiplatelet drugs and giving plasma and cold precipitation;because D-dimer was significantly elevated,the clinical pharmacists recommended anticoagulant therapy with low-molecular heparin.Due to the patient's recurrence of hemorrhagic transformation after cerebral infarction,the clinical pharmacists recommended discontinuing rivaroxaban and administering human prothrombin complex concentrate.RESULTS The physician adopted the clinical pharmacists'recommendation.After treatment,the patient's condition tended to improve steadily and was allowed to be discharged with medication.CONCLUSIONS The clinical pharmacists assessed the individualized risk and optimized the patient's medication regimen by suggesting discontinuation of antiplatelet and anticoagulant drugs,carrying out pharmaceutical care such as coagulation index monitoring,determining the time and indications for restarting anticoagulation,and pharmaceutical monitoring,to ensure the safety and efficacy of the patient's medication.
关键词
脑梗死出血转化/心房颤动/抗凝重启/药学监护/临床药师
Key words
hemorrhagic transformation after cerebral infarction/atrial fibrillation/anticoagulant restart/pharmaceutical monitoring/clinical pharmacist
维普
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