Analysis on the heterogeneity of obesity metabolic phenotypes among different populations in Bozhou,Xinjiang Uygur Autonomous Region in 2016 and 2019
Objective To explore the heterogeneity of obesity metabolic phenotypes in adults in Bozhou,Xingjiang Uygur Autonomous Region,and the variation of its distribution across different sex and age groups,so as to provide evidence for choosing target population of strengthened interventions.Methods Relevant data were collected from 5 484 adults who participated in the national health check-up in Bozhou,Xinjiang in 2016 and 2019.According to body mass index(BMI)and four metabolic indexes(blood pressure,fasting blood glucose,triglycerides and high-density lipoprotein cholesterol),the weight and metabolism of the participants were comprehensively assessed and the participants were thereby classified into metabolically healthy non-obesity(MHNO),metabolically unhealthy non-obesity(MUNO),metabolically healthy obesity(MHO)and metabolically unhealthy obesity(MUO)groups.Paired t-test and paired x2 test were used to analyze the differences in BMI,metabolic status and obesity metabolic phenotypes between 2016 and 2019 in different sex and age groups in Bozhou.Results The distribution of obesity metabolic phenotypes in the 5 484 adults in Bozhou in 2016 was 1 460(26.62%)for MHNO,2 690(49.05%)for MUNO,282(5.14%)for MHO,and 1 052(19.18%)for MUO;in 2019 was 1 387(25.29%)for MHNO,2 702(49.27%)for MUNO,288(5.25%)for MHO,and 1 107(20.19%)for MUO.By sex,the proportions of MUNO and MUO were higher in 2019 than in 2016 for men(MUNO:56.86%vs.53.48%;MUO:20.76%vs.20.43%;x2=13.753,P=0.033),and the proportions of MHO and MUO in 2019 were higher than those in 2016 for women(MHO:7.21%vs.6.27%;MUO:19.70%vs.18.12%;x2=25.814,P<0.01).As for age,the proportions of MHNO and MHO were higher in 2019 than in 2016 for those aged 40-<60 years(MHNO:38.05%vs.32.02%;MHO:8.06%vs.7.53%;x2=19.459,P=0.003),and the proportions of MUNO and MUO were higher in 2019 than in 2016 for those aged ≥60 years(MUNO:58.59%vs.55.43%;MUO:21.99%vs.20.01%;x2=48.949,P<0.01).Conclusions The overall distribution of obesity metabolic phenotypes in adults in Bozhou may be generally stable,but with obvious heterogeneity.There are differences in the distribution of obesity metabolic phenotypes over time among different sex and age groups.
Obesity metabolic phenotypeHeterogeneityHealth check-up data