首页|世界卫生组织194个成员国肺炎球菌疫苗纳入国家免疫规划现况分析

世界卫生组织194个成员国肺炎球菌疫苗纳入国家免疫规划现况分析

Analysis of the status of integration of pneumococcal vaccines into National Immunization Programs in 194 World Health Organization member countries

扫码查看
目的 分析世界卫生组织(World Health Organization,WHO)194个成员国的肺炎球菌疫苗(pneu-mococcal vaccine,PV)纳入国家免疫规划(National Immunization Program,NIP)现况,为优化调整我国PV免疫策略提供科学依据.方法 收集WHO六大区域内194个成员国的PV免疫程序、疫苗类型及目标人群接种率等公开数据,进行描述性分析.结果 在194个WHO成员国中,有163个国家至少将1种PV纳入儿童、成人或高危人群的NIP,其中156个国家将PV纳入儿童NIP,40个国家纳入高危人群NIP,28个国家纳入成人NIP.全球主要使用的3种PV中,10价肺炎球菌结合疫苗(pneumococcal conjugate vac-cine,PCV)已纳入39个国家的NIP,13价PCV已纳入133个国家的NIP,23价肺炎球菌多糖疫苗(pneu-mococcal polysaccharide vaccine,PPV)已纳入44个国家的NIP.针对儿童PCV免疫程序,147个国家采用的是3剂次免疫程序,17个国家使用4剂次免疫程序,另有2个国家采用2剂次免疫程序.全球3剂次PCV接种率从2008年的4.19%上升至2021年的50.82%.结论 基于194个WHO成员国中163个国家将PV纳入NIP及各国免疫程序和接种率现况,我国卫生行政部门应充分考虑国内肺炎球菌性疾病的负担、PV接种率、PV成本效益和PV供应等情况,加快将PV纳入我国NIP的进程,尤其是将PV纳入儿童NIP.
Objective This study aims to analyze the current status of pneumococcal vaccines(PV)in the National Immunization Program(NIP)among the 194 member countries of the World Health Organization(WHO)and provide scientific evidence for optimizing and adjusting China's PV immunization strategy.Methods Public data on PV immunization programs,vaccine types,and vaccination rates of target populations were collected from 194 member states in the six WHO regions,and descriptive analysis was performed.Results Among the 194 WHO member countries,163 countries have included at least one type of PV in their NIP for children,adults,or high-risk populations,156 countries have included PV in their NIP for children,40 countries in the high-risk population NIP,and 28 countries in the adult NIP.Among the three main PV used globally,the 10-valent pneumococcal conjugate vaccine(PCV)has been included in the NIP of 39 countries,the 13-valent PCV has been included in the NIP of 133 countries,and the 23-valent pneumococcal polysaccharide vaccine(PPV)has been included in the NIP of 44 countries.Regarding the 10-valent PCV immunization program for children,147 countries adopted the 3-dose schedule,17 countries adopted the 4-dose schedule,and two countries adopted the 2-dose schedule.The 3-dose PCV coverage has increased from 4.19%in 2008 to 50.82%in 2021.Conclusions Based on the inclusion of PV in the NIP,vaccination schedules,and coverage in 163 out of 194 WHO member countries,the health administration in our country should carefully consider the burden of pneumococcal diseases,PV coverage,cost-effectiveness,and vaccine supply.It is recommended that we expedite the process of including PV in our NIP,especially incorporating PV into the childhood NIP.

Pneumococcal vaccineWorld Health Organization(WHO)National Immunization ProgramCoverageVaccination schedule

朱丹红、随海田、张林伟、吴强松

展开 >

上海市徐汇区徐家汇街道社区卫生服务中心,上海 200030

中国生物股份有限公司

浙江省嘉兴市疾病预防控制中心

上海市徐汇区疾病预防控制中心

展开 >

肺炎球菌疫苗 世界卫生组织 国家免疫规划 接种率 免疫程序

上海市徐汇区医学科研项目

SHXH202212

2024

中国预防医学杂志
中华预防医学会

中国预防医学杂志

CSTPCD
影响因子:1.004
ISSN:1009-6639
年,卷(期):2024.25(3)
  • 20