Study on the disease burden and trend of chronic diseases related to overweight and obesity in the adult population of a divisional city in Xinjiang Production and Construction Corps
Objective To analyze the trend of chronic disease prevalence among the adult population in a division city of Xinjiang Production and Construction Corps(Xinjiang Corps)and to explore the effects of overweight and obesity on the risk of hypertension and diabetes.Methods A total of 468 404 adult participants underwent physical examinations in a hospital in a division city of Xinjiang Corps from 2018 to 2023,with sample sizes of 80 972,79 404,61 316,73 493,86 494,and 86 725 for each year.Participants who underwent continuous medical checkups for six years were selected,and 10 727 individuals were included after excluding those with baseline hypertension and diabetes in 2018 for a retrospective cohort study.Results The prevalence of obesity,central obesity,hypertension,and diabetes among the adult population in the divisional city of Xinjiang Corps showed an overall increasing trend from 2018-2023(P＜0.01).The cumulative new incidence of hypertension was 44.52％(4 776/10 727),and that of diabetes was 8.60％(923/10 727).Compared to the population with normal or underweight BMI,the overweight population had a 1.20 times higher risk of developing hypertension(HR=1.20,95％CI:1.13-1.28)and a 1.65 times higher risk of developing diabetes(HR=1.65,95％CI:1.42-1.91).The obese population had a 1.35 times higher risk of developing hypertension(HR=1.35,95％CI:1.24-1.48)and a 2.57 times higher risk of developing diabetes(HR=2.57,95％CI:2.13-3.10)compared to the underweight population.The pre-diabetic population with central obesity had a 1.22 times higher risk of developing diabetes mellitus(HR=1.22,95％CI:1.14-1.29),and the population with central obesity had a 1.08 times higher risk of developing hypertension(HR=1.08,95％CI:1.01-1.15)and a 1.89 times higher risk of developing diabetes(HR=1.89,95％CI:1.61-2.21).Conclusions The burden of four chronic diseases in the adult population of a division of Xinjiang Corps is serious,especially in the overweight and obese and centrally obese populations,highlighting the urgent need to carry out effective interventions.
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