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HPV疫苗已接种人群认知现状及影响因素分析

Current status of cognition and influencing factors among recipients of HPV vaccines

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目的 调查已接种人乳头瘤病毒(human papilloma virus,HPV)疫苗人群对于宫颈癌及HPV疫苗的认知情况,为制定已接种HPV疫苗人群宫颈癌防控策略提供参考.方法 2023年7-8月采用多阶段分层随机抽样方法,抽取鄂尔多斯市已接种HPV疫苗女性人群进行调查,调查内容包括研究对象基本信息与对HPV疫苗的认知调查两部分.采用x2检验比较不同特征调查对象的宫颈癌及HPV疫苗相关认知水平,采用多因素logistic回归分析影响认知程度的因素.结果 本研究共发放纸质问卷1 180份,剔除无效问卷93份,有效问卷1 087份,有效率92.12%.1 087名调查对象中,认知良好(≥24分)457名(42.04%)、认知不良(<24分)630名(57.96%).多因素logistic回归分析结果显示,本科及以上人群的认知程度高于高中及以下(OR=0.40,95%CI:0.25~0.65);有肿瘤家族史者高于无肿瘤家族史者(OR=0.51,95%CI:0.26~1.00);有医学背景者(OR=0.18,95%CI:0.10~0.32)高于无医学背景者;接种九价HPV疫苗者(OR=0.46,95%CI:0.28~0.76)高于接种二价疫苗者;了解HPV疫苗接种惠民政策者(OR=0.54,95%CI:0.39~0.74)高于未了解接种惠民政策者.结论 需针对低文化程度、非医学背景、低疫苗价型、不了解HPV疫苗接种惠民政策的HPV疫苗接种者开展有关宫颈癌及HPV疫苗相关健康知识教育,以提高地区HPV疫苗接种者的认知水平,降低宫颈癌的发病风险,巩固宫颈癌防控成果.
Objective The study aimed to understand the cognition of HPV vaccines and cervical cancer among women vaccinated with HPV vaccines,and to provide a reference for the prevention and control strategy of cervical cancer in this population.Methods From July to August 2023,1,087 women who had been vaccinated with the HPV vaccine in Ordos City were selected to conduct a cognitive survey on cervical cancer and HPV vaccines,using a multi-stage stratified random sampling method.The survey included the relationship between HPV infection and cervical cancer and knowledge about the HPV vaccine to prevent cervical cancer.Chi-square analysis was used to assess the cognitive level of HPV vaccine recipients with different characteristics,and multivariate logistic regression was used to analyze the influencing factors of cognitive level.Results Among 1 087 subjects,457(42.04%)scored ≥24 points(good cognition),and 630(57.96%)scored<24 points(poor cognition).The regression results showed that the cognitive degree of undergraduate and above was higher than that of senior high school and below(OR=0.40,95%CI:0.25-0.65).Those with a family history of cancer were higher than those without(OR=0.51,95%CI:0.26-1.00).Those with a medical background(OR=0.18,95%CI:0.10-0.32)were higher than those without.Those who received the nine-valent HPV vaccine(OR=0.46,95%CI:0.28-0.76)were higher than those who received the bivalent vaccine.Those who knew about the vaccination benefit policy(OR=0.54,95%CI:0.39-0.74)were higher than those who did not.Conclusions It is urgent to improve the awareness of HPV vaccine recipients about cervical cancer and the HPV vaccine,consolidate the results of cervical cancer prevention and treatment,and reduce the risk of cervical cancer by providing comprehensive health education and other intervention measures for different vaccination groups.

Human papilloma virusVaccineCervical cancerCognitive degree

张洁洁、张圣悦、郭红、刘颖、白浩、王昇、吴静

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中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京 100050

中国医科大学公共卫生学院

内蒙古医科大学公共卫生学院

鄂尔多斯市疾病预防控制中心

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人乳头瘤病毒 疫苗 宫颈癌 认知水平

2024

中国预防医学杂志
中华预防医学会

中国预防医学杂志

CSTPCD
影响因子:1.004
ISSN:1009-6639
年,卷(期):2024.25(4)