Risk factors of COVID-19 infection in Zhejiang Province,China,February-April 2020:a case-control study
Objective To identify and quantitatively assess the risk factors of coronavirus disease 2019(COVID-19)infection in Zhejiang Province,China,to provide a reference for epidemic prevention and control.Methods The onset dates from February to April 2020 of COVID-19 infections in Zhejiang Province were included and matched with an equal number of community controls.Demographic and exposure information was collected through a questionnaire,and logistic regression analysis was used to identify risk factors for infection.Results A total of 327 cases and the same number of controls were enrolled in the study.The onset dates of the cases were mainly(94.50％)in February 2020.Logistic regression analysis showed contact with COVID-19 infection(OR=221.22,95％CI:99.18-493.43),residence history in risk areas(OR=39.08,95％CI:5.32-287.01),travel history to high-risk areas(OR=28.12,95％CI:3.71-3 603.05),and exposure to healthcare facilities(OR=17.09,95％CI:7.78-37.57)were risk factors for COVID-19 infection.There were differences across occupations in the case and control group,and there was no statistical association between infection and underlying conditions.Conclusions Contact with the COVID-19 case was the primary risk factor of infection in the pre-pandemic period;a history of traveling or living in risk areas and exposure to healthcare facilities also acted as important risk factors.The principle of prevention and control measures during that period should be on the management of close contacts,screening of individuals from high-risk areas,and reducing exposure to risk areas/places.
Coronavirus disease 2019Risk factorsCase-control study
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NSTL
万方数据
