Factors influencing COVID-19 vaccine hesitancy in China:a Meta-analysis
Objective To summarize the influencing factors of vaccine hesitancy in COVID-19 vaccine and provide reference data for reducing the COVID-19 vaccine hesitancy.Methods Relevant literature on COVID-19 vaccine hesitancy and its influencing factors in mainland China from January 1,2020,to July 31,2022,was systematically searched in CNKI,Wanfang Database,VIP,SinoMed,PubMed,Embase,MEDLINE,and Cochrane Library.Meta-analysis was performed using Stata 15 software.Results A total of 19 articles were included in this study,with a total of 70 318 participants.The combined effect value of COVID-19 vaccine hesitancy was 32％(95％CI:0.25-0.38).Meta-analysis of influencing factors of vaccination showed that female(OR=1.35,95％CI:1.23-1.49),bachelor degree or above(OR=1.75,95％CI:1.31-2.33),having basic diseases(OR=1.52,95％CI:1.36-1.68),believing that COVID-19 vaccine is not necessary for health(OR=2.05,95％CI:1.66-2.52),believing that domestic risks are not high and vaccination is not necessary(OR=2.12,95％CI:1.47-3.05),believing that vaccines are risky(OR=1.57,95％CI:1.39-1.76),worrying about adverse reactions(OR=2.35,95％CI:1.83-3.01),and being influenced by family members,friends or colleagues(OR=1.55,95％CI:1.34-2.81)were the promoting factors of vaccine hesitancy(OR＞1.00,P＜0.05).However,believed in the vaccine(OR=0.55,95％CI:0.43-0.70),thought the vaccine was effective(OR=0.44,95％CI:0.38-0.52),and believed they had a high risk of COVID-19 infection(OR=0.41,95％CI:0.34-0.49)were inhibiting factors for vaccine hesitancy(OR＜1.00,P＜0.05).Conclusions People have different degrees of hesitation about the COVID-19 vaccine.It is suggested that health science education on vaccine safety,effectiveness,adverse reactions after vaccination,and precautions for vaccination be strengthened so as to improve people's trust in the vaccine and judge their own infection risks,thus reducing the degree of vaccine hesitation.
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