Comparative analysis of long-term trends in the morbidity and mortality of cervical cancer in China and the United States
Objective To compare the long-term trends of morbidity and mortality in cervical cancer between China and the United States(US),assess the effectiveness of public health control policies,and increase awareness and reduce the morbidity of cervical cancer in China.Methods This study collected data on cervical cancer age-standardized incidence rate(ASIR)and age-standardized mortality rate(ASMR)in the US and China based on public databases.The analysis was carried out using the Joinpoint Regression analysis and the age-period-cohort(APC)model.Results The ASIR for cervical cancer in the US(2000-2018,APC=-1.21％)was decreasing.In contrast,the ASIR for cervical cancer in China(2000-2014:APC=-5.20％,2004-2018:APC=0.74％)showed an increasing trend.The ASIRs showed significant period effects in the US and China,consistent with changes in incidence.The cohort effect in the United States showed a gradual decrease in the risk of incidence with birth cohort,while the cohort effect in China showed a gradual increase in the risk of incidence with birth cohort displacement.The age effect of ASIR showed that the risk of cervical cancer incidence increased from the age of 20 years both in the US and China.The ASMR of cervical cancer(2000-2018,APC=-1.03％)declined continuously in the US,while the mortality rate in China decreased from 2004 to 2009(2004-2009:APC=-2.15％)and then remained stable(2009-2018:APC=0.01％)in China.Both in the US and China,the age effects in ASMR showed the risk of mortality was positively related to age,and the period effect and cohort effect suggested the risk of mortality gradually decreased with period and birth cohort,respectively.Conclusions The burden of cervical cancer in China was much higher than that in the US.We should actively promote preventive measures for cervical cancer in the future to reduce the burden of cervical cancer.
NETL
NSTL
万方数据
