Multiple ligament knee injuries(MLKI)typically occur as a result of high-energy trauma,presenting complex conditions both in terms of pathology and treatment.Consequently,it poses significant challenges in clinical practice.In recent years,with increasing attention to MLKI,there has been extensive research on its diagnostic and treatment methods.However,despite the abundance of current research,there is no consensus on the understanding of the disease or its diagnostic and therapeutic approaches.This review provided an overview of the classification,diagnosis,treatment,and prognosis of MLKI,aiming to offer reference and new perspectives for further research and application in the diagnosis and treatment of MLKI.