Immunotherapy has become an indispensable part of cancer treatment,with the application of immune checkpoint inhibitors significantly impacting the treatment of malignant tumors.In the clinical management of colorectal carcinoma liver metastasis,there is considerable variation in the prognosis of patients undergoing immunotherapy,with some experiencing suboptimal treatment outcomes.The infiltration of immune cells in tumor tissues plays a crucial role in determining the outcome of tumor development.Therefore,gaining a deeper understanding of the interactions between tumor cells and infiltrating immune cells in the immune microenvironment of the liver is essential.Investigating the molecular mechanisms underlying the formation of the immune microenvironment in colorectal carcinoma liver metastasis can provide valuable insights and references for researching more effective treatment methods and improving patient survival outcomes.
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