Subcortical vascular cognitive impairment is a type cognitive dysfunction associated with cerebral small vessel disease and is a leading cause of Alzheimer's disease. Its exact pathogenesis remains unclear. Neurofunctional MR imaging assesses changes in the structure and function of the nervous system,providing insights into the imaging mechanisms of cognitive impairment induced by cerebral small vessel disease. Research suggests that reductions in gray matter volume,disruption of white matter integrity,and alterations in structural and functional connectivity can all impact cognitive function in patients with cerebral small vessel disease,serving as important imaging evidence for the pathogenesis of subcortical vascular cognitive impairment. Additionally,neuroimaging examinations also have significant guiding value in the early diagnosis,prognosis assessment,and treatment planning of subcortical vascular cognitive impairment in clinical practice.
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