The normal tendon-to-bone interface has complex topological isomerism characteristics,and its development and formation involve multifactorial regulation. After injury,natural repair and healing usually result in the formation of a connection between the tendon and cortical bone through newly formed fibrous scar tissue. Current research aims to achieve remodeling and regeneration of the tendon-to-bone interface by designing biomimetic scaffolds with topological isomerism characteristics and regulating the local microenvironment. The authors review the formation,remodeling,and regeneration of the tendon-to-bone interface,providing insights into the treatment of tendon-to-bone interface injuries.
关键词
骨重建/再生/腱-骨界面/重塑
Key words
Bone remodeling/Regeneration/Tendon-to-bone interface/Remodeling