Heart failure (HF) is a clinical syndrome characterized by the decompensation of cardiac function,resulting from the end stage of various heart diseases. Numerous studies have demonstrated that certain microRNAs (miRNAs) play crucial roles in the occurrence and development of cardiovascular diseases such as arrhythmias,myocardial fibrosis,and myocardial infarction. The expression of these miRNAs is closely related to the progression and adverse outcomes in HF patients,making them promising therapeutic targets for various diseases,including HF.The authors of this review discusse the biological characteristics of miRNAs and focuses on related miRNA biomarkers in the diagnosis of HF and its complications,such as chronic obstructive pulmonary disease and chronic kidney disease,with the aim of providing guidance for clinical practice.
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