首页|基于3D打印工艺的多孔植入物的设计制造及应用

基于3D打印工艺的多孔植入物的设计制造及应用

Design and Fabrication of Porous Implants Manufactured by 3D Printing

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通过有限元模拟不同类型多孔结构,进行分析并筛选出适用骨科医疗器械的多孔结构,并用3D打印技术对该多孔结构(泰森多边形结构)进行加工制造.该文对3D打印的泰森多边形多孔结构的力学性能(拉伸、压缩和弯曲)和骨长入性能进行了系统研究.力学测试结果表明,3D打印泰森多边形结构的拉伸、压缩和弯曲性能明显优于人体皮质骨,弹性模量与人体皮质骨相当.动物实验结果表明,植入比格犬后3个月,多孔结构内有明显的骨长入.该研究为多孔结构在骨植入医疗器械上的应用提供了一定的理论依据.
Different porous structures were studied through finite element analysis and then optimal porous structure was selected for the orthopedic applications.The optimal Voronoi structure was designed and fabricated using 3D printing.The mechanical properties and osseointegration ability were both investigated.The mechanical tests showed that the tensile strength,compressive strength and bending strength of Voronoi structures were obviously higher than that of the human bone,and the modulus of Voronoi structures were similar to human bone.In addition,the animal experimental results exhibited that obvious bone ingrowth was found from Month 1 to Month 6.This study provides some theoretical references for the orthopedic application of porous structures.

porous structureVoronoi3D printingmechanical testosseointegration

吴言、王聿栋、刘梦星、石杜芳、胡楠、冯伟

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中国科学院深圳先进技术研究院,深圳市,518055

国家高性能医疗器械创新中心,深圳市,518000

深圳迈瑞生物医疗电子股份有限公司,深圳市,518000

武汉迈瑞科技有限公司,武汉市,430070

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多孔结构 泰森多边形 3D打印 拉伸性能 骨长入

深圳市科技计划资助湖北省重点研发计划

JSGG202110290958000012022BAD175

2024

中国医疗器械杂志
上海市医疗器械检测所

中国医疗器械杂志

CSTPCD
影响因子:0.503
ISSN:1671-7104
年,卷(期):2024.48(1)
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