Unhealthy diet,smoking and drinking can cause a variety of pancreatic diseases,including pancreatitis,diabetes and pancreatic cancer,which seriously threaten human health.The construction of cell models in vitro is of great significance in the study of the etiology and pathogenesis of pancreatic diseases and the development and screening of medicines.At present,domestic and foreign scholars have developed a variety of in vitro pancreatic disease models.In this paper,we summarize the cell models of common pancreatic diseases in vitro,and review the characteristics,culture methods,modeling methods,and evalu-ation indexes of the model cells,so as to provide references for researchers related to pancreatic diseases.
关键词
胰腺疾病/细胞模型/细胞特性/培养方式/造模方法/评价指标
Key words
pancreatic diseases/cell model/cell characteris-tics/culture method/modeling method/evaluation index