Investigation on the depressor substance tests method of coenzyme complex for injection
Objective:To observe the acute hypotensive effect of compound coenzyme for injection on cats,and to establish a method for examination of depressor substance.Methods:Ten batches of compound coenzyme for injec-tion and histamine depressor substance were compared by cat blood pressure method to determine the limit value of depressor substance test method.According to the limit value,22 batches of samples were tested for depressor sub-stance.Results:The limit of compound coenzyme for injection was 3 IU·kg-1(calculated by coenzyme A).Two batches of 22 batches of compound coenzyme for injection did not meet the requirements.Conclusion:The method of compound coenzyme for injection is feasible according to the proposed limit value.It is suggested that the quality standard of compound coenzyme for injection should be added with the examination of depressor substance.
compound coenzyme for injectionfeline blood pressure methodhistaminelimitsdepressor sub-stancequality standard
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