首页|石墨炉原子吸收标准加入法测定血液滤过置换基础液中的铝含量

石墨炉原子吸收标准加入法测定血液滤过置换基础液中的铝含量

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目的:建立石墨炉原子吸收法测定血液滤过置换基础液中铝的含量。方法:采用石墨炉原子吸收标准加入法,加入基体改进剂,测定铝的含量。结果:铝在0~20μg·L-1范围内线性关系良好,r=0。998;检出限浓度为0。91 μg·L-1;平均回收率为96。5%。3批样品测定结果分别为3。299、1。232、2。431μg·L-1。结论:本法可有效地测定血液滤过置换基础液产品中铝的含量,对产品的原料、生产和包装等可能引入污染的途径进行控制。建议企业重视血液滤过置换基础液中铝含量的检测,尽量减小污染风险,保证产品的质量。
Determination of aluminum content in hemofiltration base solution by graphite furnace atomic absorption standard addition method
Abtract Objective:To establish a graphite furnace atomic absorption spectroscopy,and to determine the content of aluminum in the hemofiltration base solution.Methods:The standard addition method of atomic absorption of graphite furnace was used to add matrix modifier to determine the content of aluminum.Results:Aluminum has a good linear relationship in the range of 0-20 μg·L-1,r=0.998;The detection limit concentration was 0.91 μg·L-1.The average recovery rate was 96.5%.The results of the three batches were 3.299,1.232 and 2.431 µg·L-1,respectively.Conclution:This method can effectively measure the content of aluminum in hemofiltration base solution products,and control the raw materials,production and packaging of products that may introduce pollution pathways.It is recommended that enterprises pay attention to the detection of aluminum content in the on hemofil-tration base solution to minimize the risk of contamination and ensure the quality of products.

graphite furnace atomic absorption methodstandard addition methodhemofiltration basic solutionaluminumpollutionlimit control

李震、于玮洁、栾曾惠、朱韵洁、杨钊

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青岛市食品药品检验研究院,山东青岛 266000

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石墨炉原子吸收法 标准加入法 血液滤过置换基础液 污染 限度控制

2024

中国药品标准
国家药典委员会

中国药品标准

影响因子:0.372
ISSN:1009-3656
年,卷(期):2024.25(2)