目的 系统评价处方审核、治疗药物管理等药学服务的临床效益和经济性。方法 计算机检索CNKI、Web of Science、万方和PubMed数据库，检索时间为2010年1月1日至2022年10月30 日，获取有关药学服务经济性评价的文献。根据"综合卫生经济评价报告标准清单"对纳入研究进行报告学质量评价，并对相应研究结论进行汇总、整合。结果 最终纳入25篇文献，其中中国(44％)和西班牙(12％)占比较高。对于经济学报告质量，25项研究平均得分为16。6分，其中1篇文献的报告质量为优秀，17篇为良好，2篇为合格，5篇为不合格。纳人文献涉及的药学服务类型为处方审核(36％)、多种药学服务(28％)。研究结果显示，18篇(72％)表明药学服务具有临床效益和经济性，4篇(16％)显示药学服务具有临床效益但不具有经济效益，3篇(12％)研究显示药学服务未取得临床和经济效益。结论 药师服务呈现不同程度的临床效益，大多数研究支持药学服务在提升临床效果和经济效益方面的积极作用。然而，也有少部分研究表明药学服务的效果和经济性不显著。这些发现对于评估和改进药学服务的实施具有重要意义。
Systematic review of studies on the economics of different pharmacy services provided by clinical pharmacists
Objective To systematically review the clinical effectiveness and economy of services,such as prescription review and therapeutic drug management.Methods CNKI,Web of Science,Wanfang Date,and Pub Med were searched from January 1,2010,to October 30,2022,to obtain literature on the economic evaluation of pharmacy services.The quality of reporting was evaluated according to the"List of Reporting Criteria for Comprehensive Health Economic Evaluation".The conclusions of the studies were summarized and integrated.Results 25 studies were finally included,of wihich China(44％)and Spain(12％)accounted for a larger proportion.For the quality of economic reports,the mean score of 25 studies was 16.6,with 1 excellent report,17 good reports,2 qualified reports,and 5 unqualified reports.Pharmaceutical services encompassed in literature are predominantly drug review(36％),trailed by multiple pharmacy services(28％).The results of the study showed that 18(72％)of the studies indicated that the pharmacy service had clinical and economic benefits,4(16％)showed that the pharmacy service had clinical benefit but not economic benefit,and 3(12％)studies showed that the pharmacy service did not achieve clinical and economic benefits.Conclusion Pharmacist services present varying degrees of clinical benefits,and most studies support the positive role of pharmacy services in enhancing clinical outcomes and economic benefits.However,there are also a small number of studies that show insignificant effectiveness and economic benefits of pharmacy services.These findings have important implications for evaluating and improving the implementation of pharmacy services.
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