首页|某院执行国家药品集中带量采购政策对抗感染药物经济性及使用结构的影响

某院执行国家药品集中带量采购政策对抗感染药物经济性及使用结构的影响

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目的 探讨国家药品集中带量采购政策对某综合性三甲医院抗感染药物经济性及使用结构的影响,为规范临床应用管理与政策执行提供参考。方法 分析自2019年12月起国家执行1~7批集采政策后抗感染药物售价、用药频度(DDDs)、日均费用(DDDc)、实际节省费用、中选药替代率及可替代药规避率等指标。结果 带量采购政策促使该院70。73%目标药物售价降幅>70%,DDDs上涨占比69。70%,DDDc下降占比81。82%,呈"量升价降"关系占比63。64%;平均中选药替代率第1、2周期分别为84。49%、95。94%;实际节省费用第1周期平均为47。41万元,平均节省率407。60%,第2周期平均为80。31万元,平均节省率1257。04%,呈逐年上升趋势;可替代药第1周期53。85%用量上升,第2周期66。67%用量上升,年均涨幅最高为555。63%,均值为74。65%。结论 带量采购政策执行后,中选药基本取代未中选药,抗感染治疗费用大幅降低,但需加强可替代药管控,规范临床应用管理,开展中选药临床综合评价及真实世界研究。
Influence of national volume-based procurement policy on the economy and use structure of anti-infective drugs in a hospital
Objective To investigate the influence of the national volume-based procurement(NVBP)policy on the economy and use structure of anti-infective drugs in a general 3-A hospital,and to provide a reference for the standardization of clinical application management and policy implementation.Methods The price,defined daily doses(DDDs),average defined daily cost(DDDc),actual cost saving,substitution rate of selected drugs(SRSD)and avoidance rate of alternative drugs(ARAD)of anti-infective drugs before and after the implementation of 1-7 collection NVBP policy were analysed.Results The NVBP policy led to a>70%reduction in the price of 70.73%of the hospital's target drugs,69.70%of the DDDs increased,81.82%of the DDDc decreased and 63.64%showed the relationship of"volume increase and price decrease".The average SRSD was 84.49%in the first cycle and 95.94%in the second cycle.The average actual cost saving in the first cycle was 474 100 yuan,with an average saving rate of 407.60%,and in the second cycle was 803 100 yuan,with an average saving rate of 1 257.04%,showing an increasing trend year by year.The consumption of alternative drugs increased by 53.85%in the first cycle and 66.67%in the second cycle,with the highest annual increase of 555.63%,and the average of 74.65%.Conclusion After the implementation of NVBP policy,selected drugs mainly replaced unselected drugs,and the cost of anti-infection treatment was greatly reduced.However,it was necessary to strengthen the control of alternative drugs,standardize the management of clinical application,carry out clinical comprehensive evaluation of selected drugs and real world research.

National volume-based procurementAnti-infective drugsBranded drugGeneric drugPharmacy administrationDrug economyUse structure

陈泽、姚祧、金琛、李丹江、李飞、胡华

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中部战区总医院药剂科(武汉 430064)

国家药品集中带量采购 抗感染药物 原研药 仿制药 药事管理 药物经济性 使用结构

2024

中国药师
国家药品监督管理局高级研修学院,武汉医药(集团)股份有限公司

中国药师

CSTPCD
影响因子:0.944
ISSN:1008-049X
年,卷(期):2024.27(6)