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中国药物相关问题分类系统在神经内科药学监护中的应用

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目的 探讨中国药物相关问题分类系统在神经内科住院患者药学监护中的应用.方法 选取 2022 年 3-6 月浙江大学医学院附属金华医院神经内科收治的 222例住院患者为研究对象,回顾性分析临床药师工作记录.依照中国药物相关问题分类系统对药物相关问题(DRP)进行整理和分析.采用二项Logistic回归模型明确发生DRP的影响因素.结果 222 例患者中,有 76 例(34.23%)存在DRP,共识别出 104个DRP.DRP主要问题类型为治疗安全性(39.42%).DRP涉及对象均为医生,严重程度评估涉及最多的级别为"DRP到达了患者,但患者没有受到伤害"(81.73%).DRP主要原因为"药物选择"(67.31%),其次为"用法用量"(26.92%).共有 62个(59.62%)DRP的介入方案被接受,介入方案总体接受率为 87.32%.最终有 61 个(58.65%)DRP被解决.DRP涉及例次最多的药物类别为抗血小板药物.二项Logistic回归分析结果显示,用药品种数[OR=1.097,95%CI(1.030,1.167)]是神经内科住院患者发生DRP的影响因素(P<0.05).结论 神经内科住院患者DRP普遍存在.中国药物相关问题分类系统有助于临床药师对药学监护数据进行回顾和整理,总结共性问题和解决经验,提高药学监护效果.
The application of the Chinese Drug-Related Problems Classification System in neurology department pharmaceutical care
Objective To explore the application of Chinese Drug-Related Problems Classification System in the pharmaceutical care of inpatients in neurology department.Methods A total of 222 inpatients admitted to the Department of Neurology of Affiliated Jinhua Hospital,Zhejiang University School of Medicine from March to June 2022 were selected as the study subjects,and the work records of clinical pharmacists were retrospectively analyzed.The drug-related problems(DRP)were sorted and analyzed according to the Chinese Drug-Related Problems Classification System.Binomial Logistic regression model was used to analyse the influencing factors of DRP.Results Among the 222 patients,76(34.23%)had DRP and a total of 104 DRP were found.The main problem type of DRP was treatment safety(39.42%).The involving objects of DRP were all doctors.In the severity assessment,the most involved level was"DRP reached the patient,but the patient was not harmed"(81.73%).The main reason for DRP was"choice of drugs"(67.31%),followed by"usage and dosage"(26.92%).A total of 62(59.62%)DRP intervention schemes were accepted,and the overall acceptance rate of intervention schemes was 87.32%.In the end,61(58.65%)DRPs were resolved.The drug class with the largest number of DRP cases was antiplatelet drugs.Binomial Logistic regression analysis showed that the number of drug varieties[OR=1.097,95%CI(1.030,1.167)]was the influencing factor for the occurrence of DRP in neurology inpatients(P<0.05).Conclusion DRP is common in inpatients of neurology department.Chinese Drug-Related Problems Classification System is helpful for clinical pharmacists to review and sort pharmaceutical care data,summarize common problems and solving experience,and improve the effect of pharmaceutical care.

Drug-related problemsChinese Drug-Related Problems Classification SystemDepartment of neurologyPharmaceutical careClinical pharmacist

郭和坚、陈国权、朱亚兰、陈光明、陈红芳、陈刚

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浙江大学医学院附属金华医院药学部(浙江金华 321000)

浙江大学医学院附属金华医院全科医学科(浙江金华 321000)

浙江大学医学院附属金华医院神经内科(浙江金华 321000)

东台市人民医院药学科(江苏东台 224200)

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药物相关问题 中国药物相关问题分类系统 神经内科 药学监护 临床药师

浙江省公益技术应用研究计划项目金华市科技局重点科技计划项目

2016C332282023-3-116

2024

中国药师
国家药品监督管理局高级研修学院,武汉医药(集团)股份有限公司

中国药师

CSTPCD
影响因子:0.944
ISSN:1008-049X
年,卷(期):2024.27(7)