首页|四君子汤及加减方防治腹泻的药理作用与临床应用研究进展

四君子汤及加减方防治腹泻的药理作用与临床应用研究进展

扫码查看
腹泻是最常见的消化系统临床症状,其发病机制可能与肠道感染、肠道微生态失稳、肠道屏障受损等有关。四君子汤具有养胃健脾、补益气血的功效,在现代临床应用中,四君子汤加减方联合其他方剂、中医推拿、针灸或西药减毒增效,改善患者生活质量,广泛用于腹泻的治疗中,但其作用机制尚未被系统阐明。因此,从四君子汤及其加减方治疗腹泻的作用机制及临床应用的研究进展进行综述,可以为四君子汤及其加减方治疗腹泻的作用机制研究及防治提供参考。
Research progress on pharmacological action and clinical application of Sijunzi decoction and its modified formula in preventing and treating diarrhea
Diarrhea is the most common clinical symptom of the digestive system,its pathogenesis may be related to intestinal infection,intestinal microecological instability,intestinal barrier dysfunction and so on.Sijunzi decoction has the effect of invigorating spleen and nourishing stomach,and supplementing qi and blood.In modern clinical practice,modified Sijunzi decoction combining with other prescriptions,Chinese medicine massage,acupuncture and western medicine attenuates synergies,improves the patients'quality of life,and is widely used in the treatment of diarrhea,but its mechanism has not yet been systematically clarified.Therefore,this article reviews the research progress of the mechanism and clinical application of Sijunzi decoction and its modified formula in the treatment of diarrhea,and provides reference for the mechanism research and prevention of Sijunzi decoction and its modified formula in the treatment of diarrhea.

Sijunzi decoctionModified formulaDiarrheaPharmacologic actionClinical applicationGinsengLargehead atractylodes rhizomeIndian breadLiquorice root

张红伟、党文飞、周晶晶、周洁、靳子明、窦霞

展开 >

甘肃中医药大学药学院(兰州 730000)

甘肃中医药大学附属医院制剂中心(兰州 730020)

四君子汤 加减方 腹泻 药理作用 临床应用 人参 白术 茯苓 甘草

2024

中国药师
国家药品监督管理局高级研修学院,武汉医药(集团)股份有限公司

中国药师

CSTPCD
影响因子:0.944
ISSN:1008-049X
年,卷(期):2024.28(9)