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益生菌联合培土生金灸罐对腺瘤性大肠息肉术后影响

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目的 分析益生菌联合培土生金灸罐对腺瘤性大肠息肉(ACP)术后的影响。方法 纳入2021年8月至2022年5月浙江省中医院诊治的ACP患者为研究对象。采用密封信封法随机将患者分为对照组(益生菌)和试验组(益生菌联合培土生金灸罐)。本研究主要结局指标为1年ACP复发率。次要结局指标为治疗有效率及ACP术后4周和1年的中医证候积分。结果 研究最终纳入199例患者,对照组100例,试验组99例。试验组术后1年治疗有效率高于对照组(P=0。012);复发率低于对照组(P<0。05)。两组复发的患者在息肉大小和数量比较上差异无统计学意义(P>0。05)。治疗前,两组大便习惯积分、大便性质积分、便血积分、大便频率积分、腹痛积分和总积分比较差异无统计学意义(P>0。05)。两组患者术后4周和1年的大便习惯积分、大便性质积分、便血积分、大便频率积分、腹痛积分和总积分均显著低于术前(P<0。05)。试验组术后4周和1年大便习惯积分、大便性质积分、便血积分、大便频率积分、腹痛积分和总积分均低于对照组(P<0。05)。结论 益生菌联合培土生金灸罐可有效改善ACP术后中医证候积分,并降低ACP复发率。
The influence of probiotics combined with Peitu Shengjin moxibustion and cupping on postoperative patients with adenomatous colorectal polyps
Objective To analyze the postoperative effect of probiotics combined with Peitu Shengjin moxibustion and cupping on adenomatous colorectal polyps (ACP).Methods Patients with ACP diagnosed and treated in Zhejiang Provincial Hospital of Traditional Chinese Medicine from August 2021 to May 2022 were recruited as study subjects,and were divided into control group(probiotics) and test group (probiotics combined with Peitu Shengjin moxibustion and cupping).The main outcome measure of this study was the 1-year recurrence rate of ACP.The secondary outcome measures were the treatment efficiency and the traditional Chinese medicine (TCM) syndrome scores at 4 weeks and 1 year after ACP surgery.Results The study finally included 199 patients,with 100 in the control group and 99 in the test group.The 1-year postoperative treatment efficiency of the test group was higher than that of the control group (P=0.012);the recurrence rate was lower than that of the control group (P<0.05).There was no statistically significant difference in the comparison of polyp size and number between the two groups of patients with recurrence (P>0.05).Before treatment,there was no statistically significant difference between the two groups in the comparison of stool habit score,stool nature score,blood in stool score,stool frequency score,abdominal pain score and total score (P>0.05).The stool habit score,stool nature score,stool blood score,stool frequency score,abdominal pain score and total score of the patients in both groups were significantly lower than those of the preoperative period at 4 weeks and 1 year after the operation (P<0.05).Stool habit score,stool nature score,stool blood score,stool frequency score,abdominal pain score and total score were lower in the test group than in the control group at 4 weeks and 1 year postoperatively (P<0.05).Conclusion Probiotics combined with Peitu Shengjin moxibustion and cupping can effectively improve the TCM syndrome scores after ACP surgery and reduce the recurrence rate of ACP.

ProbioticsPeitu ShengjinMoxibustion and cuppingColorectal polypsTCM syndrome scores

李秀燕、陈超、杨丹华、蔡利军

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浙江中医药大学附属第一医院(浙江省中医院)消化科,杭州 310006

益生菌 培土生金法 灸罐 大肠息肉 中医证候积分

2024

中国药师
国家药品监督管理局高级研修学院,武汉医药(集团)股份有限公司

中国药师

CSTPCD
影响因子:0.944
ISSN:1008-049X
年,卷(期):2024.28(10)