134例宫颈上皮内瘤变患者HPV分型检测结果分析
Study on the types of human papillomavirus of 135 cases in cervical intraepitheliai neoplasia and cervical carcinoma
王琳倩 1李萍 1吴楠1
作者信息
摘要
目的 探讨宫颈上皮内瘤变(CIN)中不同类型人乳头瘤病毒(HPV)的感染及分型情况.方法 回顾性研究北京军区总医院妇科门诊134例已经确诊的CIN患者,采用凯普的核酸分子快速导流杂交基因芯片技术对HPV进行分型.结果 1.各级别CIN以HPV高危亚型单一或者多重感染为主;2.在HPV阳性的101例患者中,单一感染者73例(72.28％),双重感染者24例(23.76％),三重感染者3例(2.97％),四重感染者1例(0.99％)；3.HPV - 16、58感染率最高,分别为30.83％,24.06％.结论 HPV感染以高危型和多重感染为主；随CIN级别的增高,HPV阳性率也是增高的；HPV - 16亚型的感染率最高.
Abstract
Objective: To study the infection condition of different types of Human papilloma virus in cervical intraepitheliai neoplasia (CIN). Methods; A total of 134 gynecological outpatients in The Military General Hospital of Beijing who were confirmed to have CIN were studied. The HybriMax were used to detect HPV genotypes. Results:, All levels of CIN is main infected with single or multiple high risk HPV genotypes. 2. In 102 HPV positive patients, single infected patients is 74 cases (72. 28% ) , double infected patients is 24 cases (23.76% ) , triple infected patients is 3 cases (2.97% ) , quadruple patients infected is 1 case (0.99% );3. The infected rate of HPV -16, 58 is the hightest, 30.83% and 24.06% respectively. Conclusion; The main infected HPV is the high risk and multiple genotypes. As the CIN types increaseing, the positive HPV is increasing too. The infection of HPV -16 types is the highest.
关键词
人乳头瘤病毒/宫颈上皮内瘤变Key words
Human papilloma virus/Cervical intraepitheliai neoplasia引用本文复制引用
出版年
2012
NETL
NSTL
维普
万方数据