首页|基于主成分分析法的新疆乌鲁木齐子痫前期孕产妇妊娠风险与妊娠结局研究

基于主成分分析法的新疆乌鲁木齐子痫前期孕产妇妊娠风险与妊娠结局研究

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目的 探索乌鲁木齐市子痫前期对孕妇及新生儿结局的影响.方法 回顾性收集2021年2月至2023年2月乌鲁木齐市妇幼保健院分娩的子痫前期患者1000例作为子痫前期组,选取同期产检无子痫前期孕妇4308例作为对照组,采用单因素比较分析子痫前期组与对照组的妊娠结局.利用主成分分析法消除各因素之间的相关性,运用Logistic回归进行妊娠结局分析.结果 子痫前期组与对照组妊娠结局与并发症比较,子痫前期组不良妊娠结局与并发症的发生率高于子痫前期组,子痫前期组不同分娩方式妊娠结局比较,剖宫产的胎儿不良妊娠结局发生率高于自然分娩;子痫前期组足月产与早产妊娠结局比较,早产不良妊娠结局发生率高于足月产不良妊娠结局;通过主成分分析子痫前期组妊娠结局中所有变量相关情况,共提取了 3个公因子,累计贡献率达到67.413%.结论 子痫前期对孕妇及新生儿结局造成了不良影响,子痫前期与胎儿生长发育迟缓呈正相关关系,子痫前期孕妇发生绒毛膜羊膜炎会更容易发生产褥期感染、早产、产后出血等不良妊娠结局,应尽早采取干预措施预防其进一步进展,做到早发现、早干预、早治疗,改善母婴结局.
Study on pregnancy risk and pregnancy outcome of pregnant women with preeclampsia in Urumqi City of Xinjiang based on principal component analysis approach
Objective To explore the impact of preeclampsia on maternal and neonatal outcomes in Urumqi.Methods 1000 cases of preeclamptic patients delivered in Urumqi Maternal and Child Health Hospital from February 2021 to February 2023 were retrospectively collected as the preeclampsia group,and 4308 cases of pregnant women without preeclamp-sia in the same period of obstetrics examination were selected as the control group,and the pregnancy outcomes of the preec-lampsia group and the normal group were analyzed by one-way comparison.The correlation between the factors was eliminated by principal component analysis,and the pregnancy outcomes were analyzed by Logistic regression.Results Comparing the pregnancy outcomes and complications between the preeclampsia group and the normal group,the incidence of adverse pregn-ancy outcomes and complications was higher in the preeclampsia group than in the preeclampsia group.Comparing the pregnancy outcomes of the preeclampsia group with different modes of delivery,the incidence of fetal adverse pregnancy outcomes was higher in cesarean section than in spontaneous delivery;and comparing the pregnancy outcomes of the pree-clampsia group with those of the full-term and preterm deliveries,the incidence of preterm deliveries was higher than that of the term deliveries.By analyzing the correlation of all variables in pregnancy outcomes in the preeclampsia group through principal component analysis,a total of three common factors were extracted with a cumulative contribution of 67.413%.Conclusion Pre-eclampsia adversely affects maternal and neonatal outcomes,and there is a positive correlation between pre-eclampsia and fetal growth retardation.Pre-eclamptic pregnant women with chorioamnionitis are more likely to have adverse pregnancy outcomes such as puerperal infections,preterm labor,and post-partum hemorrhage,so early interven-tion should be taken to prevent its further progression,and to achieve early detection,intervention,and treatment,so as to improve the outcomes of mothers and infants.

preeclampsiapregnancy outcomemode of deliveryprincipal component analysis

程备、段茉莉、丁桂凤

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新疆医科大学公共卫生学院,新疆乌鲁木齐 830000

乌鲁木齐市妇幼保健院,新疆乌鲁木齐 830000

子痫前期 妊娠结局 分娩方式 主成分分析

新疆维吾尔自治区自然科学基金

2022D01A29

2024

中国优生与遗传杂志
中国优生科学协会

中国优生与遗传杂志

CSTPCD
影响因子:0.527
ISSN:1006-9534
年,卷(期):2024.32(3)
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