中性粒细胞外诱捕网在抗磷脂综合征中作用的研究进展
Research progress of the role of neutrophil extracellular traps in antiphospholipid syndrome
张烨潇 1徐霖婕 1乌兰1
作者信息
- 1. 南京医科大学附属妇产医院/南京市妇幼保健院妇产科,江苏南京 210004
- 折叠
摘要
抗磷脂综合征(APS)是一种系统性自身免疫性疾病,以血栓形成或产科并发症为主要特征.最近越来越多的证据表明,中性粒细胞,尤其是中性粒细胞外诱捕网(NETs)在APS的致病过程中发挥着重要作用.本文对NETs在APS中的作用进行了综述,旨在帮助人们更好地了解APS的发病机制,从而制定更有效、更个性化的治疗方案.
Abstract
Antiphospholipid syndrome(APS),a systemic autoimmune disease,is principally characterized by thrombosis and obstetric complications.Recently,increasing evidence shows that neutrophils,especially neutrophil extracel-lular traps(NETs)play a crucial role in pathological process of APS.In order to help understand the pathogenesis of APS,this article makes a literature review for the role of NETs in APS,thus helps to institute more effective and personalized heal pro-ject.
关键词
抗磷脂综合征/中性粒细胞外诱捕网/中性粒细胞/抗磷脂抗体/产科并发症Key words
antiphospholipid syndrome/neutrophil extracellular traps/neutrophils/antiphospholipid antibodies/ob-stetric complications引用本文复制引用
出版年
2024
NETL
NSTL
万方数据