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近足月-足月儿生后早期肺部生理征象的超声特征分析

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目的 研究足月儿或近足月儿生后早期"宫内-宫外"转换期间肺部超声图像特征和变化规律.方法 采集2019年4-12月于复旦大学附属妇产科医院出生的466名足月儿或近足月儿肺部超声图像.检查的时间点为生后0.5 h、1.0 h、2.0h和4.0h;保留3 d后未发生肺部疾病的新生儿作为研究对象,回顾性分析他们出生时采集的图像.结果 最终纳入393例无肺部疾病新生儿的肺部超声图像,分别有109例于生后0.5 h;107例于生后1.0 h;141例于生后2.0 h;36例于生后4.0 h采集超声图像.无肺部疾病的足月儿或近足月儿肺部超声的征象主要有3种:"单纯A-线""散在B-线"和"融合B-线".其中"融合B-线"和"散在B-线"随时间逐渐减少(P<0.001);而"单纯A-线"则逐渐增多(P<0.001).生后1 h内有两例新生儿出现"融合B线",分别于生后0.5 h和1h各有1例.结论 肺部超声可以动态观察足月儿或近足月儿生后早期肺部生理征象,主要有3种:"单纯A-线""散在B-线"和"融合B-线".需要被临床医生所重视,以免造成过度治疗.
Lung ultrasound characteristics of late preterm and term infants shortly after birth
Objective To observe the characteristics and evolution of lung ultrasound images in late preterm and term infants during the intrauterine-to-extrauterine environmental transition stage.Methods Lung ultrasound images of 466 late preterm or term neonates born in Obstetrics and Gynecology Hospital ofFudan University from April to December 2019 were collected.Lung ultrasound was performed at one of following timings after birth:0.5 h,1.0 h,2.0 h and 4.0 h and images were saved.The neonates without the respiratory system disorders(conformed by a three-day follow-up)were enrolled in.Their images were retrospectively analyzed.Results A total of 393 neonates without the respiratory system diseases were eligible.The number of images was 109,107,141,and 36 of 0.5 h,1.0 h,2.0 h,and 4.0 h after birth.We found mainly three signs in their images:"A-line","Distribute B-line"and"Coalesced B-line".While the number of"Distribute B-line"and"Coalesced B-line"were decreased(P<0.001),"A-line"were increased over the time(P<0.001).The"Coalesced B-line"sign was found in two infants,respectively at 0.5 h and 1 h.Conclusion LUS is available to observe the physiological images of the late pre-term and term infants shortly after birth.The most common characteristics include"A-line","Distribute B-line"and"Coa-lesced B-line".These clues may be useful to avoid unnecessary treatment in LUS guided treatment protocol.

lungultrasoundterm infantslate preterm infantsphysiological sign

张睿洁、郤冠楠、林昕奥、樊晓波、汪吉梅

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复旦大学附属妇产科医院新生儿科,上海 200001

超声检查 足月儿 近足月儿 生理征象

上海市卫生健康委项目

202040402

2024

中国优生与遗传杂志
中国优生科学协会

中国优生与遗传杂志

CSTPCD
影响因子:0.527
ISSN:1006-9534
年,卷(期):2024.32(4)