首页|内蒙古地区不同妊娠期孕妇血清维生素A、D、E水平的检测分析

内蒙古地区不同妊娠期孕妇血清维生素A、D、E水平的检测分析

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目的 检测内蒙古地区孕妇不同妊娠期维生素A、D、E水平,尤其是异常率的分析,以便临床上有针对性地为内蒙古地区孕妇合理补充维生素提供理论支持.方法 选取2022年8月至10月在内蒙古自治区妇幼保健院进行产前保健的1292例孕妇为研究对象.采用HPLC-MS/MS检测不同妊娠期孕妇血清维生素A、D、E水平,进行统计分析,计算其异常率.结果 本研究孕妇血清维生素A、D、E的分布范围(95%CI)分别为(355.03~367.77)ng/mL、(14.2~14.85)ng/mL、(7089.97~7375.39)ng/mL,相应缺乏率分别为 30.42%、98.30%、16.64%,维生素 A、E 过量的孕妇占比仅为0.77%和0.15%,维生素D无过量者.其中:妊娠早期的孕妇维生素A、D、E异常率分别为30.77%、98.82%、19.34%;妊娠中期的孕妇维生素A、D、E异常率分别为28.84%、97.18%、11.29%;妊娠晚期的孕妇维生素A、D、E异常率分别为62.16%、94.59%、0%.经分析,不同妊娠时期的孕妇血清维生素A、D、E的含量及异常率有统计学意义(P<0.05).结论 内蒙古地区孕妇维生素A、D、E缺乏严重,异常率偏高.
Detection and analysis on vitamin A,D,and E levels in serum of pregnant women at different pregnancy stages in Inner Mongolia
Objective The purpose of this paper is to detect the level of vitamin A,D,E and especially analyze ab-normal rate in different gestational period of pregnant women in Inner Mongolia so as to provide theoretical support for the rational vitamin supplementation of pregnant women in the area.Methods 1292 pregnant women who received prenatal care at Inner Mongolia Maternity and Child Health Care Hospital from August to October 2022 have been selected as the research subjects.HPLC-MS/MS method is used to detect serum levels of vitamin A,D,and E in pregnant women of different gesta-tional periods,conducting statistical analysis,and calculating their abnormal rates.Results The distribution range(95%CI)of serum vitamins A,D,and E in this study were(355.03-367.77)ng/mL,(14.2-14.85)ng/mL,and(7089.97-7375.39)ng/mL,respectively,where deficiency rates correspond with 30.42%,98.30%,and 16.64%,respectively.Pregnant women with exces-sive levels of vitamin A and E accounted for only 0.77%and 0.15%,in addition,none of them had excessive levels of vitamin D.Among them,in early pregnancy,the abnormal rates of vitamin A,D,and E were 30.77%,98.82%,and 19.34%,respec-tively;in mid pregnancy,the abnormal rates of vitamin A,D,and E were 28.84%,97.18%,and 11.29%,respectively;in the late pregnancy,the abnormal rates of vitamin A,D,and E were 62.16%,94.59%,and 0%,respectively.The levels and abnor-mal rates of serum vitamin A,D,and E in pregnant women at different stages of pregnancy were statistically significant(P<0.05).Conclusion The deficiency of vitamin A,D and E in pregnant women in Inner Mongolia is serious,and the abnor-mal rate is high.

Inner Mongoliapregnant womenvitamin Avitamin Dvitamin E

张美玲、侯东霞、朱博、王虹、秦磊、王艳、高娜、康文光、王晓华

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内蒙古医科大学研究生院,内蒙古呼和浩特 010110

内蒙古自治区妇幼保健院遗传优生科,内蒙古呼和浩特 010020

内蒙古 孕妇 维生素A 维生素D 维生素E

内蒙古自治区"草原英才"工程高层次培养人才项目

CYYC012074

2024

中国优生与遗传杂志
中国优生科学协会

中国优生与遗传杂志

CSTPCD
影响因子:0.527
ISSN:1006-9534
年,卷(期):2024.32(6)