珍稀濒危药用植物贺兰山丁香资源概况、化学成分和药理作用研究进展
Research Progress on Resources Survey,Chemical Constituents and Pharmacological Action of Endangered Mongolian Medicinal Plant Syringa pinnatifolia var.alaschanensis
朱文菁 1张宇娟 1张烨 1陈苏依勒 2苏云 3陈文婧 1张锦乔 1岳鑫 1马月宏4
作者信息
- 1. 内蒙古医科大学 药学院,内蒙古 呼和浩特 010010
- 2. 阿拉善盟蒙医医院,内蒙古 阿拉善左旗 750306
- 3. 内蒙古贺兰山国家级自然保护区管理局,内蒙古 阿拉善左旗 750306
- 4. 内蒙古医科大学 基础医学院,内蒙古 呼和浩特 010010
- 折叠
摘要
目的:综述珍稀濒危药用植物贺兰山丁香的资源概况、用药沿革、化学成分以及药理作用研究进展,以期为其资源保护和可持续利用奠定基础.方法:借助爱如生基本古籍库、中国知网、SciFinder、GeenMedicial等中外文数据库,查阅贺兰山丁香的资源概况、用药沿革、化学成分以及药理作用相关文献资料,梳理归纳,并形成综述.结果:贺兰山丁香是羽叶丁香在贺兰山地区特有变种,是国家三级重点保护珍稀濒危植物,以粗枝和根入蒙药,蒙药名阿拉善-阿嘎如,又名山沉香,用于胸闷气短、心肌缺血等心肺疾病.山沉香富含挥发油类、木质素类、萜类化合物等成分,具有治疗心肌缺血、抗血小板凝集、抗氧化、镇静、镇痛、抗炎、抗菌等药理活性,常作为沉香替代品.结论:珍稀濒危药用植物贺兰山丁香入药历史悠久且疗效确切,亟待开展可持续利用研究.
Abstract
Objective:The resource survey,historical evolution,chemical composition and pharmaco-logical action of rare and threatened medicinal plant Syringa pinnatifolia var.alaschanensis were re-viewed in this study,in order to provide a basis for its resource protection and sustainable utilization.Methods:By the aid of the Erudition's Basic Ancient Chinese Books Library,China National Knowl-edge Infrastructure,SciFinder,GeenMedicial and other Chinese and foreign databases,the resource survey,historical evolution,chemical composition and pharmacological action of S.pinnatifolia var.alaschanensis were combed and concluded.Results:S.pinnatifolia var.alaschanensis was a unique va-riety of pinnate lilac found in the Helan Mountain area.It was a rare and threatened national tertiary im-portant protection plant.With thick branches and roots into Mongolian medicine,the Mongolian medi-cine was called Alashan Agaru.It was used for chest discomfort,shortness of breath,myocardial isch-emia and other cardiopulmonary disease.S.pinnatifolia var.alaschanensis was rich in volatile oil,lig-nan,terpenoids and other compositions.It had pharmacological activities such as treatment of myocar-dial ischemia,anti-platelet aggregation,anti-oxidant,sedation,analgesia,anti-inflammatory,anti-bacterial and so on.It was often used as a substitute for agarwood.Conclusion:The rare and threatened Mongolian medicinal plant S.pinnatifolia var.alaschanensis had a long history medicinal application and definite therapeutic effect,which urgent needed to do development research on sustainable utiliza-tion.
关键词
蒙药/贺兰山丁香/基源植物/濒危植物/化学成分/药理活性Key words
Mongolian medicine/Syringa pinnatifolia var.alaschanensis/Original plant/Endan-gered plants/Chemical constituents/Pharmacological action引用本文复制引用
基金项目
内蒙古自治区科技计划(2022YFHH0135)
内蒙古自治区自然科学基金(2021MS08160)
内蒙古医科大学科技百万项目(YKD2020KJBW012)
内蒙古医科大学科技百万项目(YKD2018KJBW022)
内蒙古医科大学博士启动金项目(KD2017BQ004)
出版年
2024