Hypericum perforatum L.was one of the traditional Chinese medicines in China,which was used in clinical practice as"Xiaoqiao"in Forsythia suspensa before the Song Dynasty.It was the root-bearing whole grass of"H.perforatum"today.It had the effects of convergence hemostasis,heat-clear-ing and detoxifying,dampness and so on.The chemical constituents mainly included flavonoids,phlo-roglucinols,naphthodianthrones,volatile oils,phenolic acids,etc.Modern pharmacological studies had shown that H.perforatum had anti-depressant,antibacterial,anti-tumor,liver protection and anti-fibrosis effects.The mechanism of its pharmacological action was relatively complex,and some mecha-nisms needed to be further studied.This article reviewed the literature on the historical evolution,chemical constituerts,quality control and pharmacological action of H.perforatum,in order to provide reference and basis for the expansion of the medicinal parts and subsequent in-depth development and research of H.perforatum.
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