摘要
目的:探究从无花果中提取的果胶对皮肤的美白和保护作用.方法:采用复合酶解结合热水浸提法提取无花果中的果胶成分,通过自由基清除试验、抑制酪氨酸酶和弹性蛋白酶能力以及结合斑马鱼模式生物美白试验共同分析无花果果胶对皮肤美白、抗衰老和抗皱活性影响.结果:当无花果果胶浓度为2 mg/mL时,对斑马鱼胚黑色素和酪氨酸酶的抑制率分别达到84.8%和76.1%,具有较高抑制黑色素和酪氨酸酶活性的作用.自由基清除率和弹性蛋白酶的抑制率均随着无花果果胶浓度的增加而提高,分别达85.4%和68.7%.结论:本研究提取的无花果果胶具有较好的抗自由基、抑制酪氨酸酶和弹性蛋白酶活性作用,有望应用于抗衰老、美白淡斑、抗皱等护肤类化妆品中.
Abstract
Objective:To investigate the skin whitening and protective effects of pectin extracted from Ficus carica.Methods:Compound enzymatic hydrolysis combined with hot distilled water method was applied for the extraction of F.carica pectin.The anti-aging,whitening,and anti-wrinkle activi-ties of F.carica pectin on the skin were evaluated through various analyses,including free radical scav-enging rates,inhibition of tyrosinase and elastase,and a biological whitening experiment of zebrafish model.Results:As extracted F.carica pectin concentration reached 2 mg/mL,the inhibition rates of melanin and tyrosinase in zebrafish embryos were significant by 84.8%and 76.1%,respectively.Fur-thermore,the free radical clearance rate and elastase inhibition rate were also enhanced with higher concentrations of F.carica pectin,reaching 85.4%and 68.7%.Conclusion:F.carica pectin demon-strated excellent free radical scavenging activity,as well as inhibition of tyrosinase and elastase.There-fore,it held promise for application in skincare cosmetics aimed at anti-aging,whitening,and anti-wrinkle effects.
维普
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