Objective:The extraction process and preparation technology of Compound Dendrobium Po-lygonatum sibiricum Granules were optimized.Methods:The extraction rate of polysaccharide was used as the index to optimize the extraction process of Compound Dendrobium Polygonatum sibiricum Gran-ules,and preparation technology was evaluated with the inspection index of hygroscopicity,solubility,molding rate,and angle of repose.Results:The optimal extraction process were as follows:solid to liquid ratio 1∶23(g/mL),time 132.3 min,temperature 76.8℃.The optimal preparation process were lactose to dextrin ratio of 2.38∶1,the ratio of excipients to extract was 3.36∶1.Conclusion:The ex-periment showed that the optimized preparation techniques were stable and reliable,which provided a re-liable basis for the industrial production of Compound Dendrobium Polygonatum sibiricum Granules.
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