Sophorae Flavescentis Radix is a commonly used traditional Chinese medicine in clinical practice,widely used and with great development prospects.However,there is limited research on the historical evolution and related research processing currently.In order to further develop and ex-plore Sophorae Flavescentis Radix processing products,this study summarized and organized the con-tent of Sophorae Flavescentis Radix processing recorded in ancient and modern literature.It was found that most ancient books that recorded Sophorae Flavescentis Radix processing methods were concen-trated in the Song and Qing dynasties,and their processing methods were diverse,mainly using vine-gar boiling,wine boiling,steaming rice and swill juice soaking,stir frying yellow,charcoal frying,and wine frying.Nowadays,various processing methods were basically no longer used,and in clinical practice,raw and charcoal products were mostly used as medicine,especially raw products.In some regions,there was still a lack of accurate and controllable quality standards for Sophorae Flavescentis Radix and its processed products in the processing standards.The compilation of modern scientific research achievements on the chemical composition,medicinal properties,pharmacological effects,and other aspects of Sophorae Flavescentis Radix before and after processing,could provide reference for related research on Sophorae Flavescentis Radix.