Objective To explore the influencing factors of intracranial hemorrhage in elderly patients with acute occlusion of intracranial arteries after treatment and reperfusion.Methods A retrospective selection was conducted on elderly patients with acute occlusion of the intracranial artery who were treated at the Hebei Petro China Central Hospital from February 2019 to May 2021.Sixty patients who received mechanical thrombectomy treatment were selected as the observation group,and 60 patients who received combined arterial and venous thrombolysis treatment were selected as the control group.The vascular reperfusion rate and incidence of intracranial hemorrhage were observed and compared between the two groups.Meanwhile,multiple logistic regression analysis was used to identify the influencing factors of intracranial hemorrhage.Results The reperfusion rate of the observation group's blood vessels was 85.00％(51/60),significantly higher than the control group's 68.33％(41/60),and the difference was statistically significant(x2=4.658,P=0.031).The National Institutes of Health Neurological Deficit Score(NIHSS)of the observation group after treatment was(10.57±2.23),significantly lower than that of the control group(14.73±2.84),and the difference was statistically significant(P＜0.05).The reperfusion rate of blood vessels in patients under 80 years old in the observation group was significantly higher than that in patients ≥80 years old(P＜0.05).The results of univariate analysis showed that there were statistically significant differences in age,NIHSS at admission,Alberta Stroke Program Early CT Score(ASPECTS),and neutrophil absolute value/lymphocyte ratio(NLR)between patients with and without intracranial hemorrhage(all P＜0.05);Multivariate logistic regression analysis showed that age(OR=1.756,95％CI:1.184-2.604)and NIHSS at admission(OR=2.392,95％CI:1.401-4.084)were risk factors for postoperative intracranial hemorrhage in elderly patients with acute occlusion of the large intracranial artery,while ASPECTS(OR=0.364,95％CI:0.190-0.697)was a protective factor.Conclusions Mechanical thrombectomy has good clinical efficacy in the treatment of elderly patients with acute occlusion of intracranial arteries,and is worthy of clinical use;The intracranial hemorrhage after reperfusion is mainly influenced by the patient's age,NIHSS at admission,and ASPECTS.
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