Comparison of clinical characteristics and long-term prognosis between patients with deep infiltrating endometriosis and those without deep infiltrating endometriosis
Objective To compare and analyze the clinical characteristics and long-term prognosis of patients with deep infiltrating endometriosis(DIE)and non deep infiltrating endometriosis.Methods A retrospective analysis was conducted on the data of 178 patients with endometriosis who underwent laparoscopic surgery at the General Hospital of Northern Theater Command from January 2016 to January 2018.Among them,95 patients with DIE were treated as the observation group,and 83 patients with non deep infiltration were treated as the control group.Both groups were followed up for at least 5 years after surgery.Perform statistical analysis on the general clinical data,intraoperative and postoperative follow-up data of the two groups.Results Compared with the control group,the observation group had significantly older age[(33.8±5.5)years vs(32.0±5.2)years],moderate to severe dysmenorrhea[72.6％(69/95)vs 55.4％(46/83)],chronic pelvic pain[24.2％(23/95)vs 8.4％(7/83)],higher proportion of elevated blood carbohydrate antigen 125(CA125)[80.0％(76/95)vs 65.1％(54/83)],and higher Visual Analogue Scale(VAS)[(5.4±1.2)points vs(4.3±0.9)points];At the same time,the surgery time was longer[(75.1±20.1)min vs(56.0±18.9)min],the patient's intraoperative bleeding was also greater[(79.2±23.0)ml vs(57.8±16.3)min],bilateral cysts[54.7％(52/95)vs 34.9％(29/83)],severe pelvic adhesions[90.5％(86/95)vs 53.0％(44/83)],and the proportion of concurrent adenomyosis[41.1％(39/95)vs 22.9％(19/83)]was higher,with higher Revised American Fertility Society(rAFS)scores[(61.8±22.1)vs(39.4±19.1)].The proportion of rAFS stage Ⅳ[71.6％(68/95)vs 43.4％(36/83)]was higher,and the proportion of postoperative medication was higher[98.9％(94/95)vs 92.8％(7/83)].The above indicators showed statistically significant differences between the two groups(all P＜0.05 or P＜0.01).There was no statistically significant difference in the recurrence rate[21.1％(20/95)vs 15.7％(13/83)]and live birth rate[100％(35/35)vs 92.1％(35/38)]between the observation group and the control group(all P＞0.05).Conclusions Compared to non DIE patients,DIE patients have more severe pain symptoms and pelvic adhesions,higher rAFS scores,and a higher proportion of stage.Ⅳ.However,there was no significant difference in postoperative recurrence rate,and there was no significant impact on fertility outcomes.
维普
万方数据
