The TMEM family is widely distributed in the plasma membrane and organelle membrane,and has multiple biological functions.The TMEM family has different functions and mechanisms of action in different diseases.Recent research shows that TMEM family members play an important role in the pathogenesis of non tumor diseases,especially in cardiovascular,respiratory and nervous system diseases,such as atherosclerosis,Parkinson's disease,depression,etc.This article reviews the mechanism of action of the TMEM family in non tumor diseases,which is of great significance for further revealing the disease mechanism and elucidating the biological functions of TMEM family members,and provides a new perspective for disease treatment strategies.
维普
万方数据