腺样囊性癌动物模型的研究进展
Research progress on animal models of adenoid cystic carcinoma
柳睿 1马建民1
作者信息
- 1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼视光与视觉科学重点实验室,北京 100730
- 折叠
摘要
腺样囊性癌(ACC)是头颈部常见的恶性肿瘤,具有较高的神经侵袭率、局部复发率和远处转移率,预后较差.动物模型是研究肿瘤发病机制和有效药物的理想模型,本文总结了国内外近些年来头颈部涎腺和泪腺ACC动物模型的建立方法和优缺点,为合理选择和优化动物模型奠定基础.
Abstract
Adenoid cystic carcinoma(ACC)is a common malignant tumor in the head and neck,with a high rate of neuroinvasion,local recurrence,and distant metastasis,and a poor prognosis.Animal models are ideal models for studying the pathogenesis of tumors and effective drugs.This article summarizes the methods and advantages and disadvantages of establishing animal models for head and neck salivary and lacrimal gland ACC in recent years,laying a foundation for the rational selection and optimization of animal models.
关键词
癌,腺样囊性/涎腺/泪腺/模型,动物Key words
Carcinoma,adenoid cystic/Salivary glands/Lacrimal gland/Models,animal引用本文复制引用
基金项目
北京市自然科学基金(7222025)
北京市科技新星计划交叉合作课题(20220484218)
北京市医院管理中心"登峰"计划(DFL20190201)
出版年
2024
NETL
NSTL
万方数据