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肾动脉型大动脉炎介入治疗的疗效

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目的 探讨肾动脉型大动脉炎介入治疗的疗效。方法 回顾性分析2012年1月至2023年7月首都医科大学宣武医院收治的26例(28条血管)累及肾动脉的大动脉炎患者的临床资料,采用球囊扩张或支架植入术,随访观察患者的血管通畅率、血压变化情况、手术效果及并发症情况。结果 所有患者施行球囊扩张或支架植入术,手术均获得成功,其中球囊扩张23例(25条血管),支架植入3例(3条血管)。随访12~102个月,在随访过程中1例于术后57个月死于肾功能衰竭(单侧肾动脉球囊扩张病例),1例在第1年失访(单侧肾动脉球囊扩张病例)。球囊扩张的血管1年、3年及5年的通畅率分别为23/24(95。83%),22/24(91。67%),20/23(86。96%)。支架植入的患者随访1年有2条病变血管通畅,随访3年有1条病变血管通畅。部分患者临床症状得到改善,其中高血压症状治愈3例(3/26,11。54%),改善19例(19/26,73。08%),无效4例(4/26,15。38%),收缩压从术前的(169。29±10。76)mmHg降到(150。31±14。62)mmHg,差异有统计学意义(P<0。05)。血肌酐术前(78。42±21。38)μmol/L,术后(77。83±21。14)μmol/L,差异无统计学意义(P>0。05)。结论 血管腔内成形术治疗累及肾动脉的大动脉炎患者安全、可行,疗效肯定。
The efficacy of interventional treatment for Takayasu arteritis involved renal artery
Objective To explore the therapeutic effect of interventional treatment on Takayasu arteritis involved renal artery.Methods A retrospective analysis was conducted on the clinical data of 26 patients(28 blood vessels)with Takayasu arteritis involved renal artery admitted to the Xuanwu Hospital,Capital University of Medical Sciences from January 2012 to July 2023.Balloon dilation or stent implantation were performed,and the t vascular patency rate,blood pressure changes,surgical effects,and complications were followed up and observed.Results All patients underwent balloon dilation or stent implantation,and the surgery was successful,including 23 cases of balloon dilation(25 blood vessels)and 3 cases of stent implantation(3 blood vessels).During the follow-up period of 12-102 months,one case died of renal failure at 57 months post surgery(unilateral renal artery balloon dilation case),and one case was lost in the first year(unilateral renal artery balloon dilation case).The patency rates of balloon dilated blood vessels at 1 year,3 years,and 5 years were 23/24(95.83%),22/24(91.67%),and 20/23(86.96%),respectively.Patients with stent implantation had 2 diseased blood vessels unobstructed at 1 year of follow-up and 1 diseased blood vessel unobstructed at 3 years of follow-up.Some patients showed improvement in clinical symptoms,including 3 cases(3/26,11.54%)of cured hypertension symptoms,19 cases(19/26,73.08%)of improved symptoms,and 4 cases(4/26,15.38%)of ineffective symptoms.The systolic blood pressure decreased from preoperative(169.29±10.76)mmHg to(150.31±14.62)mmHg,with a statistically significant difference(P<0.05).There was no statistically significant difference in blood creatinine levels between preoperative(78.42±21.38)μmol/L and postoperative(77.83±21.14)μmol/L(P>0.05).Conclusions Endovascular angioplasty is safe,feasible,and has a definite therapeutic effect on patients with Takayasu's arteritis involved renal artery.

Takayasu arteritisRenal arteryAngioplastyEndovascular interventional therapy

刘一人、谷涌泉、郭连瑞

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首都医科大学宣武医院血管外科,北京 100053

大动脉炎 肾动脉 血管成形术 介入治疗

国家重点研发计划项目国家重点研发计划项目

2021YFC25005042022YFC3602404

2024

中国医师杂志
中华医学会 湖南省医学会

中国医师杂志

CSTPCD
影响因子:0.876
ISSN:1008-1372
年,卷(期):2024.26(6)